Evidence map›Paper›PMID 30186353›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2018

Paeonol Ameliorates Ovalbumin-Induced Asthma through the Inhibition of TLR4/NF-

Yongjun Tang, Weihua Huang, Qianqian Song, Xiangrong Zheng, Ruohui He, Jie Liu

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Association of the Toll-like receptor 4 and NOX4 gene and protein levels in asthmatic patients with metabolic syndrome: A case-control study.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2023
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Protective Effects of Platycodin D3 on Airway Remodeling and Inflammation via Modulating MAPK/NF-Evidence-based complementary and alternative medicine : eCAM · 2022
    Article
  12. Improvement of Bronchial Immune Hypersensitivity Reaction Using Extracts fromEvidence-based complementary and alternative medicine : eCAM · 2021
    Article
  13. Article
  14. Evidence-based complementary and alternative medicine : eCAM · 2020
    Review
  15. Article
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yongjun TangDepartment of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China.
Weihua HuangDepartment of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China.ORCID 0000-0003-4167-8304
Qianqian SongDepartment of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China.
Xiangrong ZhengDepartment of Pediatrics, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China.
Ruohui HeDepartment of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China.
Jie LiuDepartment of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China.ORCID 0000-0001-8883-5712
Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Asthma is a chronic inflammatory disease of the airways, with complex signaling pathways involved in its pathogenesis. It was reported that paeonol attenuated airway inflammation of ovalbumin (OVA)-induced mice. Therefore, it is of importance to further investigate the underlying mechanism. BALB/c mice were challenged with OVA for the asthma model, which was validated by the changed levels of IL-4, IFN-

Identifiers

PMID30186353
PMCPMC6114069
OpenAlexW2887425241

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.