Evidence map›Paper›PMID 30186318›Full record

ArticleNeural plasticity2018

Antidepressant Effects of Probucol on Early-Symptomatic YAC128 Transgenic Mice for Huntington's Disease.

Cristine de Paula Nascimento-Castro, Ana Claudia Wink, Victor Silva da Fônseca, Claudia Daniele Bianco, Elisa C Winkelmann-Duarte, Marcelo Farina, Ana Lúcia S Rodrigues, Joana Gil-Mohapel, Andreza Fabro de Bem, Patricia S Brocardo

Open access · goldAbstract read
In one paragraph

Article in Neural plasticity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Cristine de Paula Nascimento-CastroDepartment of Morphological Sciences, Center of Biological Sciences, Universidade Federal de Santa Catarina, 88040-900 Florianópolis, SC, Brazil.ORCID 0000-0003-1435-8006
Ana Claudia WinkDepartment of Morphological Sciences, Center of Biological Sciences, Universidade Federal de Santa Catarina, 88040-900 Florianópolis, SC, Brazil.ORCID 0000-0002-8176-2765
Victor Silva da FônsecaDepartment of Morphological Sciences, Center of Biological Sciences, Universidade Federal de Santa Catarina, 88040-900 Florianópolis, SC, Brazil.ORCID 0000-0001-5872-4018
Claudia Daniele BiancoDepartment of Morphological Sciences, Center of Biological Sciences, Universidade Federal de Santa Catarina, 88040-900 Florianópolis, SC, Brazil.ORCID 0000-0002-3152-6895
Elisa C Winkelmann-DuarteDepartment of Morphological Sciences, Center of Biological Sciences, Universidade Federal de Santa Catarina, 88040-900 Florianópolis, SC, Brazil.ORCID 0000-0001-7846-7063
Marcelo FarinaDepartment of Biochemistry, Center of Biological Sciences, Universidade Federal de Santa Catarina, 88040-900 Florianópolis, SC, Brazil.ORCID 0000-0001-8255-8515
Ana Lúcia S RodriguesDepartment of Biochemistry, Center of Biological Sciences, Universidade Federal de Santa Catarina, 88040-900 Florianópolis, SC, Brazil.
Joana Gil-MohapelDivision of Medical Sciences, UBC Island Medical Program, University of Victoria, Victoria, BC, Canada V8W 2Y2.ORCID 0000-0003-4982-1662
Andreza Fabro de BemDepartment of Biochemistry, Center of Biological Sciences, Universidade Federal de Santa Catarina, 88040-900 Florianópolis, SC, Brazil.ORCID 0000-0003-1090-5244
Patricia S BrocardoDepartment of Morphological Sciences, Center of Biological Sciences, Universidade Federal de Santa Catarina, 88040-900 Florianópolis, SC, Brazil.ORCID 0000-0002-1680-5909
Universidade Federal de Santa Catarina · BRUniversidade de Brasília · BRUniversity of Victoria · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder caused by a trinucleotide expansion in the

Indexed as

AnimalsAntidepressive AgentsAntioxidantsCell DifferentiationCell ProliferationCholesterolCorpus StriatumDepressionDisease Models, AnimalDoublecortin ProteinFemaleHippocampusHuntington DiseaseMaleMice, TransgenicMotor ActivityAntidepressive AgentsAntioxidantsCholesterolDcx protein, mouseDoublecortin ProteinProbucol

Identifiers

PMID30186318
PMCPMC6112232
OpenAlexW2887319556

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.