Evidence map›Paper›PMID 30186247›Full record

ArticleFrontiers in microbiology2018

The Potential Role of the Dipeptidyl Peptidase-4-Like Activity From the Gut Microbiota on the Host Health.

Marta Olivares, Valentina Schüppel, Ahmed M Hassan, Martin Beaumont, Audrey M Neyrinck, Laure B Bindels, Alfonso Benítez-Páez, Yolanda Sanz, Dirk Haller, Peter Holzer and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 1 synthesis or guideline pooled it, 69 citations in OpenAlex.

  1. Pooled it
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  5. Begelomab (BEGESANDJournal of clinical medicine · 2026
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  19. Celiac Disease: A Review from Genetic to Treatment.Iranian biomedical journal · 2024
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 4 countries.

Marta OlivaresMetabolism and Nutrition Research Group, Louvain Drug Research Institute, Université catholique de Louvain, Brussels, Belgium.
Valentina SchüppelZIEL Institute for Food and Health, Technical University of Munich, Freising-Weihenstephan, Germany.
Ahmed M HassanResearch Unit of Translational Neurogastroenterology, Pharmacology Section, Otto Loewi Research Center, Medical University of Graz, Graz, Austria.
Martin BeaumontMetabolism and Nutrition Research Group, Louvain Drug Research Institute, Université catholique de Louvain, Brussels, Belgium.
Audrey M NeyrinckMetabolism and Nutrition Research Group, Louvain Drug Research Institute, Université catholique de Louvain, Brussels, Belgium.
Laure B BindelsMetabolism and Nutrition Research Group, Louvain Drug Research Institute, Université catholique de Louvain, Brussels, Belgium.
Alfonso Benítez-PáezMicrobial Ecology, Nutrition and Health Research Unit, Institute of Agrochemistry and Food Technology, Spanish National Research Council (IATA-CSIC), Valencia, Spain.
Yolanda SanzMicrobial Ecology, Nutrition and Health Research Unit, Institute of Agrochemistry and Food Technology, Spanish National Research Council (IATA-CSIC), Valencia, Spain.
Dirk HallerZIEL Institute for Food and Health, Technical University of Munich, Freising-Weihenstephan, Germany.
Peter HolzerResearch Unit of Translational Neurogastroenterology, Pharmacology Section, Otto Loewi Research Center, Medical University of Graz, Graz, Austria.
Nathalie M DelzenneMetabolism and Nutrition Research Group, Louvain Drug Research Institute, Université catholique de Louvain, Brussels, Belgium.
UCLouvain · BEMedical University of Graz · ATConsejo Superior de Investigaciones Científicas · ESInstituto de Agroquímica y Tecnología de Alimentos · ESLeibniz-Institute for Food Systems Biology at the Technical University of Munich · DESolvay (Belgium) · BETechnical University of Munich · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Dipeptidyl peptidase-4 (DPP-4) activity influences metabolic, behavioral and intestinal disorders through the cleavage of key hormones and peptides. Some studies describe the existence of human DPP-4 homologs in commensal bacteria, for instance in

Indexed as

behaviorDPP-4 activitygut microbiotametabolismmicrobiomePepX activity

Identifiers

PMID30186247
PMCPMC6113382
OpenAlexW2888489814

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.