Evidence map›Paper›PMID 30186181›Full record

ArticleFrontiers in pharmacology2018

Emodin Attenuates Lipopolysaccharide-Induced Acute Liver Injury via Inhibiting the TLR4 Signaling Pathway

Yan Ding, Pan Liu, Zhi-Lin Chen, Shao-Jun Zhang, You-Qin Wang, Xin Cai, Lei Luo, Xuan Zhou, Lei Zhao

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. The Invasive SpeciesFrontiers in pharmacology · 2022
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Hepatoprotective Effect of Kaempferol-A Review.Molecules (Basel, Switzerland) · 2025
    Review
  7. Review
  8. Article
  9. Nutraceutical Potential of Djulis (Antioxidants (Basel, Switzerland) · 2024
    Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Ethyl Acetate Extract fromMolecules (Basel, Switzerland) · 2022
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yan DingDepartment of Infectious Diseases and Immunology, Wuhan Children's Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Pan LiuSchool of Clinical Medicine, Hubei University of Chinese Medicine, Wuhan, China.
Zhi-Lin ChenDepartment of Infectious Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Shao-Jun ZhangNational and Local Joint Engineering Research Center for High-throughput Drug Screening Technology, Hubei Collaborative Innovation Center for Green Transformation of Bio-resources, Hubei University, Wuhan, China.
You-Qin WangGraduate School of Jinzhou Medical University, Department of Pediatrics, Renmin Hospital, Hubei University of Medicine, Shiyan, China.
Xin CaiSchool of Clinical Medicine, Hubei University of Chinese Medicine, Wuhan, China.
Lei LuoSchool of Clinical Medicine, Hubei University of Chinese Medicine, Wuhan, China.
Xuan ZhouDepartment of Infectious Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Lei ZhaoDepartment of Infectious Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

acute liver injuryemodinlipopolysaccharidesignaling pathwayTLR4

Identifiers

PMID30186181
PMCPMC6113398

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.