Evidence map›Paper›PMID 30186164›Full record

ArticleFrontiers in pharmacology2018

Cannabidiol Administered During Peri-Adolescence Prevents Behavioral Abnormalities in an Animal Model of Schizophrenia.

Fernanda F Peres, Mariana C Diana, Raquel Levin, Mayra A Suiama, Valéria Almeida, Ana M Vendramini, Camila M Santos, Antônio W Zuardi, Jaime E C Hallak, José A Crippa and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 3 pooled it
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 3 syntheses or guidelines pooled it, 50 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2020
    Pooled it
  4. Low-Dose Cannabidiol Treatment does not Alter Cognitive Performance in the HIV-1 Transgenic Rat Model of NeuroHIV.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2026
    Article
  5. Tissue-specific untargetedFrontiers in pharmacology · 2026
    Article
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  14. Article
  15. [Neurodevelopment and cannabis].Bulletin de l'Academie nationale de medecine · 2020
    Review
  16. Article
  17. Review
  18. Article
  19. Preclinical and Clinical Evidence Supporting Use of Cannabidiol in Psychiatry.Evidence-based complementary and alternative medicine : eCAM · 2019
    Review
  20. Cannabidiol as a potential treatment for psychosis.Therapeutic advances in psychopharmacology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Fernanda F PeresDepartment of Pharmacology, Federal University of São Paulo, São Paulo, Brazil.
Mariana C DianaDepartment of Pharmacology, Federal University of São Paulo, São Paulo, Brazil.
Raquel LevinDepartment of Pharmacology, Federal University of São Paulo, São Paulo, Brazil.
Mayra A SuiamaDepartment of Pharmacology, Federal University of São Paulo, São Paulo, Brazil.
Valéria AlmeidaDepartment of Pharmacology, Federal University of São Paulo, São Paulo, Brazil.
Ana M VendraminiDepartment of Pharmacology, Federal University of São Paulo, São Paulo, Brazil.
Camila M SantosDepartment of Pharmacology, Federal University of São Paulo, São Paulo, Brazil.
Antônio W ZuardiNational Institute for Translational Medicine, National Council for Scientific and Technological Development, Ribeirão Preto, Brazil.
Jaime E C HallakNational Institute for Translational Medicine, National Council for Scientific and Technological Development, Ribeirão Preto, Brazil.
José A CrippaNational Institute for Translational Medicine, National Council for Scientific and Technological Development, Ribeirão Preto, Brazil.
Vanessa C AbílioDepartment of Pharmacology, Federal University of São Paulo, São Paulo, Brazil.
Universidade Federal de São Paulo · BRNational Council for Scientific and Technological Development · BRUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Schizophrenia is considered a debilitating neurodevelopmental psychiatric disorder and its pharmacotherapy remains problematic without recent major advances. The development of interventions able to prevent the emergence of schizophrenia would therefore represent an enormous progress. Here, we investigated whether treatment with cannabidiol (CBD - a compound of

Indexed as

animal modelsBDNFcannabidiolpreventionschizophreniaserotoninSHR strainside effects

Identifiers

PMID30186164
PMCPMC6113576
OpenAlexW2888479212

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.