Evidence map›Paper›PMID 30186149›Full record

ArticleFrontiers in aging neuroscience2018

Blood-Cerebrospinal Fluid Barrier Gradients in Mild Cognitive Impairment and Alzheimer's Disease: Relationship to Inflammatory Cytokines and Chemokines.

Brian R Ott, Richard N Jones, Lori A Daiello, Suzanne M de la Monte, Edward G Stopa, Conrad E Johanson, Charles Denby, Paula Grammas

Open access · goldAbstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 2 pooled it
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 2 syntheses or guidelines pooled it, 92 citations in OpenAlex.

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  19. Systemic inflammation, neuroinflammation and perioperative neurocognitive disorders.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Brian R OttDepartment of Neurology, Alpert Medical School of Brown University, Rhode Island Hospital, Providence, RI, United States.
Richard N JonesDepartment of Neurology, Alpert Medical School of Brown University, Rhode Island Hospital, Providence, RI, United States.
Lori A DaielloDepartment of Neurology, Alpert Medical School of Brown University, Rhode Island Hospital, Providence, RI, United States.
Suzanne M de la MonteGeorge & Anne Ryan Institute for Neuroscience, University of Rhode Island, Kingston, RI, United States.
Edward G StopaGeorge & Anne Ryan Institute for Neuroscience, University of Rhode Island, Kingston, RI, United States.
Conrad E JohansonDepartment of Neurosurgery, Alpert Medical School of Brown University, Rhode Island Hospital, Providence, RI, United States.
Charles DenbyDepartment of Neurology, Alpert Medical School of Brown University, Rhode Island Hospital, Providence, RI, United States.
Paula GrammasGeorge & Anne Ryan Institute for Neuroscience, University of Rhode Island, Kingston, RI, United States.
Rhode Island Hospital · USBrown University · USUniversity of Rhode Island · US

Funding

Ethanol, IRS-1 Signaling and Neuronal MigrationR37AA011431 · NIAAA · RHODE ISLAND HOSPITAL · PI DE LA MONTE, SUZANNE M. · 2009 to 2018
$3.7M
EFFECTS OF ETHANOL ON INSULIN SIGNALING IN THE BRAINR01AA012908 · NIAAA · RHODE ISLAND HOSPITAL (PROVIDENCE, RI) · PI DE LA MONTE, SUZANNE M. · 2003 to 2013
$3.0M
NIAAA NIH HHS R01 AA012908NIAAA NIH HHS R37 AA011431
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Alzheimerblood brain barrierchoroid plexusinflammationmild cognitive impairment (MCI)

Identifiers

PMID30186149
PMCPMC6110816
OpenAlexW2888307926

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.