ArticleIndian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine2018
The Platelet Count and its Implications in Sickle Cell Disease Patients Admitted for Intensive Care.
Article in Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06601894 (The Relationship of Platelet Counts With Sickle Cell Anemia in the Eastern Region of Saudi Arabia), which is not on this map. Cited by 14 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Relationship of Platelet Counts With Sickle Cell Anemia in the Eastern Region of Saudi Arabia
Who cites it
14 citing papers in PubMed, 33 citations in OpenAlex.
- Platelets in sickle cell disease: biomarkers, mediators, and lessons from clinical trials.Blood vessels, thrombosis & hemostasis · 2026Review
- Predictors of Acute Chest Syndrome in Patients With Sickle Cell Disease: A Cross-Sectional Observational Study.Cureus · 2026Article
- Haematological Profile of Patients with Sickle Cell Disease in the Acholi Sub-Region, Uganda.Journal of blood medicine · 2026Article
- Can platelet to neutrophil ratio (PNR) serve as a viable alternative tool for monitoring sickle cell disease patients on hydroxyurea in low income countries?Annals of hematology · 2025Article
- Polymorphic Distribution of Human Homeostatic Iron Regulator Gene H63D rs1799945 and Clinico-Hematological Parameters of Sickle Cell Anemia Patients: A Case-Control Study in Northern Ghana.Health science reports · 2025Article
- Reference intervals of haematological indices for young adults with sickle cell anaemia in Southwestern Nigeria.BMC research notes · 2025Article
- Multi-center study on mortality in children, and adults with sickle cell anemia-risk factors and causes of death.Scientific reports · 2024Article
- Laboratory predictors of sickle cell disease severity: a cross-sectional study.Journal of medicine and life · 2024Article
- Predictors of Intensive Care Admission Among Adult Patients with Sickle Cell Disease in Eastern Province of Saudi Arabia.Journal of blood medicine · 2023Article
- Article
- [Platelet count in the steady state phase and clinical severity of sickle cell disease in a reference centre for sickle cell disease in Mali].The Pan African medical journal · 2022Article
- Detection of BCL11A and HBS1L-MYB Genotypes in Sickle Cell Anemia.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2020Article
- Changes in Blood Profile from Steady State in Patients with Sickle Cell Anemia Admitted for Vaso-occlusive Crisis and Acute Chest Syndrome.Advances in hematology · 2020Article
- Spirometry Patterns in Adult Sickle Cell Disease: A Retrospective Observational Study.Saudi journal of medicine & medical sciencesArticle
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsIn sickle cell disease (SCD) patients admitted for intensive care, evaluation of platelet counts in different types of sickle cell complications and its prognostic relevance are not well-studied. Illuminating these aspects were the objectives of this study. MATERIALS AND
methodsA chart review of 136 adult SCD patients consecutively admitted to our Intensive Care Unit (ICU) was done. The prognosis on day 1 was assessed by Acute Physiology and Chronic Health Evaluation (APACHE II) and multiple organ dysfunction scores (MODS). Receiver operating characteristic (ROC) curves evaluated the ability of platelet counts, MODS, and APACHE II scores to predict survival.
resultsThe most common types of crises were severe pain (
conclusionsIn severe sickle cell crisis thrombocytopenia is more common than thrombocytosis. In the ICU, day 1 platelet counts correlate inversely with prognostic scores and are significantly reduced in multi-organ failure and nonsurvivors. A platelet count above 175 × 10
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