ArticleNature2018
In vivo reprogramming of wound-resident cells generates skin epithelial tissue.
Abstract read
In one paragraph
Article in Nature, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers.
0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
72 citing papers in PubMed.
- Ectomesenchyme contributes to epidermal stem cell formation through mesenchymal-to-epithelial transition.Nature communications · 2026Article
- Skin aging: mechanisms, evaluation, and rejuvenation.The EMBO journal · 2026Review
- Interleukin-10 Derived Apoptotic Vesicles Enhance Scarless Skin Healing by Modulating Fibroblast Metabolism and Fibrosis Pathways.Cell proliferation · 2026Article
- The role and mechanism by which micropeptide WHPP promote refractory wound healing.Journal of translational medicine · 2026Article
- Mitochondrial mGPDH Modulates Fibroblast Function in Diabetic Wound Healing via the SIRT1-c-Myc-TGF-β1 Axis.Diabetes · 2026Article
- Scar Inhibition in Wound Healing: Mechanisms, Design, and Recent Advances.Exploration (Beijing, China) · 2026Review
- Reprogramming the wound microenvironment: identity remodeling strategies for fibroblasts, keratinocytes, and macrophages.Frontiers in immunology · 2026Review
- Direct Lineage Reprogramming of Fibroblasts into Functional Keratinocyte-Like Cells via BMI1 and FGFR2b for Diabetic Wound Repair.Stem cell reviews and reports · 2025Article
- Chemical reprogramming ameliorates cellular hallmarks of aging and extends lifespan.EMBO molecular medicine · 2025Article
- TFcomb identifies transcription factor combinations for cellular reprogramming based on single-cell multiomics data.Genome research · 2025Article
- Weekly Intraperitoneal Injection of Tamoxifen in an Inducible In Vivo Model of Junctional Epidermolysis Bullosa Generates Early and Advanced Disease Phenotypes.JID innovations : skin science from molecules to population health · 2025Article
- Bioengineering strategies for regeneration of skin integrity: A literature review.Regenerative therapy · 2025Review
- Direct fibroblast reprogramming: an emerging strategy for treating organic fibrosis.Journal of translational medicine · 2025Review
- The Effects of M2 Macrophages-Derived Exosomes on Urethral Fibrosis and Stricture in Scar Formation.ImmunoTargets and therapy · 2025Article
- DNA methylation in mammalian development and disease.Nature reviews. Genetics · 2025Review
- Enhanced Wound Healing and Autogenesis Through Lentiviral Transfection of Adipose-Derived Stem Cells Combined with Dermal Substitute.Biomedicines · 2024Article
- In vivo gene editing of T-cells in lymph nodes for enhanced cancer immunotherapy.Nature communications · 2024Article
- A cooling wound dressing for accelerating healing under sunlight.Innovation (Cambridge (Mass.)) · 2024Review
- Advances and applications of biomimetic biomaterials for endogenous skin regeneration.Bioactive materials · 2024Review
- Discovering human cell-compatible gene therapy virus variants via optimized screening in mouse models.Cell proliferation · 2024Article
12 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
19 authors.
Masakazu KuritaThe Salk Institute for Biological Studies, La Jolla, CA, USA.
Toshikazu AraokaThe Salk Institute for Biological Studies, La Jolla, CA, USA.
Tomoaki HishidaThe Salk Institute for Biological Studies, La Jolla, CA, USA.
David D O'KeefeThe Salk Institute for Biological Studies, La Jolla, CA, USA.
Yuta TakahashiThe Salk Institute for Biological Studies, La Jolla, CA, USA.
Akihisa SakamotoThe Salk Institute for Biological Studies, La Jolla, CA, USA.
Masahiro SakuraiThe Salk Institute for Biological Studies, La Jolla, CA, USA.
Keiichiro SuzukiThe Salk Institute for Biological Studies, La Jolla, CA, USA.
Jun WuThe Salk Institute for Biological Studies, La Jolla, CA, USA.
Mako YamamotoThe Salk Institute for Biological Studies, La Jolla, CA, USA.
Reyna Hernandez-BenitezThe Salk Institute for Biological Studies, La Jolla, CA, USA.
Alejandro OcampoThe Salk Institute for Biological Studies, La Jolla, CA, USA.
Pradeep ReddyThe Salk Institute for Biological Studies, La Jolla, CA, USA.
Maxim Nikolaievich ShokhirevThe Razavi Newman Integrative Genomics & Bioinformatics Core, The Salk Institute for Biological Studies, La Jolla, CA, USA.
Pierre MagistrettiKing Abdullah University of Science & Technology (KAUST), Thuwal, Saudi Arabia.
Estrella Núñez DelicadoUniversidad Católica San Antonio de Murcia (UCAM), Campus de los Jerónimos, Guadalupe, Spain.
Hitomi EtoDepartment of Plastic Surgery, Kyorin University School of Medicine, Tokyo, Japan.
Kiyonori HariiDepartment of Plastic Surgery, Kyorin University School of Medicine, Tokyo, Japan.
Juan Carlos Izpisua BelmonteThe Salk Institute for Biological Studies, La Jolla, CA, USA. belmonte@salk.edu.
Funding
Viral Vector Core (VVC)P30CA014195 · NCI · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI Ye Zheng · 1985 to 2026
$82.8MNCI NIH HHS P30 014195NCI NIH HHS P30 CA014195
Abstract
Large cutaneous ulcers are, in severe cases, life threatening
Indexed as
Cellular ReprogrammingAnimalsCell LineageEpithelial CellsFemaleFibroblastsGene Expression ProfilingHumansKeratinocytesMaleMesenchymal Stem CellsMiceRegenerative MedicineSkinSkin UlcerTranscription FactorsTranscription Factors
Identifiers
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.