Evidence map›Paper›PMID 30185902›Full record

ArticleScientific reports2018

Body mass index modulates the association between CDKAL1 rs10946398 variant and type 2 diabetes among Taiwanese women.

Oswald Ndi Nfor, Ming-Fang Wu, Chun-Te Lee, Lee Wang, Wen-Hsiu Liu, Disline Manli Tantoh, Shu-Yi Hsu, Kuan-Jung Lee, Chien-Chang Ho, Tonmoy Debnath and 2 more

Abstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Molecular Effects of Physical Activity and Body Composition: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2025
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Interactive Effect ofDiabetes, metabolic syndrome and obesity : targets and therapy · 2020
    Article
  10. Review
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  12. Type 2 Diabetes-Associated Genetic Polymorphisms as Potential Disease Predictors.Diabetes, metabolic syndrome and obesity : targets and therapy · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Oswald Ndi NforDepartment of Public Health and Institute of Public Health, Chung Shan Medical University, Taichung City, Taiwan.
Ming-Fang WuSchool of Medicine, Chung Shan Medical University, Taichung City, Taiwan.
Chun-Te LeeSchool of Medicine, Chung Shan Medical University, Taichung City, Taiwan.
Lee WangDepartment of Public Health and Institute of Public Health, Chung Shan Medical University, Taichung City, Taiwan.
Wen-Hsiu LiuDepartment of Public Health and Institute of Public Health, Chung Shan Medical University, Taichung City, Taiwan.
Disline Manli TantohDepartment of Public Health and Institute of Public Health, Chung Shan Medical University, Taichung City, Taiwan.
Shu-Yi HsuDepartment of Public Health and Institute of Public Health, Chung Shan Medical University, Taichung City, Taiwan.
Kuan-Jung LeeDepartment of Public Health and Institute of Public Health, Chung Shan Medical University, Taichung City, Taiwan.
Chien-Chang HoDepartment of Physical Education, Fu-Jen Catholic University, New Taipei City, Taiwan.
Tonmoy DebnathDepartment of Public Health and Institute of Public Health, Chung Shan Medical University, Taichung City, Taiwan.ORCID 0000-0001-5842-1121
Chia-Chi LungDepartment of Public Health and Institute of Public Health, Chung Shan Medical University, Taichung City, Taiwan.
Yung-Po LiawDepartment of Public Health and Institute of Public Health, Chung Shan Medical University, Taichung City, Taiwan. Liawyp@csmu.edu.tw.ORCID 0000-0003-2046-4964

Funding

Ministry of Science and Technology, Taiwan (Ministry of Science and Technology of Taiwan) MOST 105-2627-M-040-002
6 · The paper itself

Abstract

CDKAL1 rs10946398 is a type 2 diabetes (T2D)-associated variant. It is a new body mass index (BMI)-associated variant in Asian populations. We investigated the association between rs10946398 and T2D among 9908 participants aged 30-70 years based on BMI: normal weight; 18.5 ≤ BMI < 24 kg/m

Indexed as

Polymorphism, Single NucleotideAdultAgedBody Mass IndexDiabetes Mellitus, Type 2FemaleHumansMaleMiddle AgedRisk FactorsSex FactorsTaiwantRNA MethyltransferasesCDKAL1 protein, humantRNA Methyltransferases

Identifiers

PMID30185902
PMCPMC6125600

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.