ReviewEuropean journal of clinical nutrition2018
Body composition and insulin resistance in children.
Review in European journal of clinical nutrition, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05701813 (Effects of Inositols on Insulin Resistance in Children With Obesity), which is not on this map. Cited by 48 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Inositols on Insulin Resistance in Children With Obesity (ONIRICO Trial)
Who cites it
48 citing papers in PubMed, 2 syntheses or guidelines pooled it, 84 citations in OpenAlex.
- Body composition after allogeneic haematopoietic cell transplantation/total body irradiation in children and young people: a restricted systematic review.Journal of cancer survivorship : research and practice · 2020Pooled it
- Effects of Nutritional Education Interventions on Metabolic Risk in Children and Adolescents: A Systematic Review of Controlled Trials.Nutrients · 2019Pooled it
- Effects of a Family-Based Lifestyle Intervention Plus Supervised Exercise Training on Abdominal Fat Depots in Children With Overweight or Obesity: A Secondary Analysis of a Nonrandomized Clinical Trial.JAMA network open · 2022Trial
- Association of Waist Circumference and Body Composition Indices with Insulin Resistance in Prepubertal Children with Obesity.Metabolites · 2026Article
- Insulin resistance in school-age children: comparison surrogate diagnostic markers.Pediatric research · 2026Article
- Associations Between Handgrip Strength and Markers of Insulin Resistance and Inflammation in Childhood and Adolescence: A Systematic Review With Meta-Analysis.Translational sports medicine · 2026Review
- Cardio-Metabolic Risk in Adults Born Preterm: A Narrative Review.Journal of clinical medicine · 2025Review
- Markers of body fat, the mediating role of alanine aminotransferase, and their association with the risk of metabolic dysfunction-associated steatotic liver disease.European journal of pediatrics · 2025Article
- Fatty Acids in Childhood Obesity: A Link Between Nutrition, Metabolic Alterations and Cardiovascular Risk.Journal of lipid and atherosclerosis · 2025Article
- Bile acids: potential links to overweight/obesity and androgen levels in pubertal girls.Frontiers in endocrinology · 2025Article
- The development of an attention mechanism enhanced deep learning model and its application for body composition assessment with L3 CT images.Scientific reports · 2024Article
- [Secular trend in growth of Uygur primary and middle school students aged 7-18 years in Xinjiang from 1985 to 2019].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2024Article
- Exploring the Link between Oxidative Stress, Selenium Levels, and Obesity in Youth.International journal of molecular sciences · 2024Review
- The potential of the Mediterranean diet to improve metabolic control and body composition in youths with Type 1 Diabetes Mellitus.BMC endocrine disorders · 2024Article
- Trajectories of lifestyle patterns from 2 to 8 years of age and cardiometabolic risk in children: the GUSTO study.The international journal of behavioral nutrition and physical activity · 2024Article
- Menarche age and the risk of diabetes: A cross-sectional study in South-Eastern Iran.Health science reports · 2024Article
- The relative contributions of soft tissue mass components as risk or protective factors of non-alcoholic fatty liver disease in children.European journal of clinical nutrition · 2023Article
- Serum levels of the novel adipokine isthmin-1 are associated with obesity in pubertal boys.World journal of pediatrics : WJP · 2023Article
- Mediation Analysis of Waist Circumference in the Association of Gut Microbiota with Insulin Resistance in Children.Children (Basel, Switzerland) · 2023Article
- Fasting indices of glucose-insulin-metabolism across life span and prediction of glycemic deterioration in children with obesity from new diagnostic cut-offs.The Lancet regional health. Europe · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Insulin resistance is a condition of gluco-metabolic sufferance that may hesitate in the further development of type 2 diabetes and cardiovascular disease. The development of insulin resistance is mostly associated with the accumulation of excessive fat in the body. The epidemic impact of obesity in the youngest promoted an increase of the prevalence of insulin resistance also in children and adolescents. Increased fat accumulation in the peri-visceral area of the abdomen, occurring preferably at and after puberty, and in the liver, as non-alcoholic fatty liver disease, plays a role in the process. After puberty, males are at higher risk than females to develop insulin resistance. Also ethnicity contributes to sensitivity of children to develop insulin resistance, where Hispanics, South-Asians, and Indians are at higher risk than Whites and Blacks.In spite of the research progress in the field, several questions on the relationship between body composition and insulin resistance are still unanswered. Multiomics approach, combined with nutrition as well as imaging techniques might contribute to unravel the role of body composition on insulin resistance.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.