Evidence map›Paper›PMID 30185618›Full record

ArticleThe Journal of biological chemistry2018

Multi-tiered pairing selectivity between E2 ubiquitin-conjugating enzymes and E3 ligases.

Ilona Turek, Nadine Tischer, Roman Lassig, Marco Trujillo

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
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  9. Article
  10. Functional Characterization of PotatoInternational journal of molecular sciences · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Root Membrane Ubiquitinome under Short-Term Osmotic Stress.International journal of molecular sciences · 2022
    Article
  15. Article
  16. Emerging Roles of Non-proteolytic Ubiquitination in Tumorigenesis.Frontiers in cell and developmental biology · 2022
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ilona TurekFrom the Leibniz Institute of Plant Biochemistry, Independent Junior Research Group, Weinberg 3, 06120 Halle (Saale) and.
Nadine TischerFrom the Leibniz Institute of Plant Biochemistry, Independent Junior Research Group, Weinberg 3, 06120 Halle (Saale) and.
Roman LassigFrom the Leibniz Institute of Plant Biochemistry, Independent Junior Research Group, Weinberg 3, 06120 Halle (Saale) and.
Marco TrujilloFrom the Leibniz Institute of Plant Biochemistry, Independent Junior Research Group, Weinberg 3, 06120 Halle (Saale) and marco.trujillo@bio.uni-freiburg.de.ORCID 0000-0002-5470-7277
Leibniz Institute of Plant Biochemistry · DEUniversity of Freiburg · DE

Funding

Core-010UL1TR001073 · NCATS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI KELLER, MARLA J, SHAMOON, HARRY · 2013 to 2017
$21.3M
NCATS NIH HHS UL1 TR001073
6 · The paper itself

Abstract

Ubiquitination is a prevalent post-translational modification involved in all aspects of cell physiology. It is mediated by an enzymatic cascade and the E2 ubiquitin-conjugating enzymes (UBCs) lie at its heart. Even though E3 ubiquitin ligases determine the specificity of the reaction, E2s catalyze the attachment of ubiquitin and have emerged as key mediators of chain assembly. They are largely responsible for the type of linkage between ubiquitin moieties and thus, the fate endowed onto the modified substrate. However,

Indexed as

UbiquitinationArabidopsis ProteinsImmunity, InnateMutant ProteinsProtein BindingUbiquitin-Conjugating EnzymesUbiquitin-Protein LigasesArabidopsis ProteinsMutant ProteinsPUB22 protein, ArabidopsisUBC13A protein, ArabidopsisUBC13B protein, ArabidopsisUbiquitin-Conjugating EnzymesUbiquitin-Protein Ligasescell signalingE3 ubiquitin ligaseinnate immunityubiquitinubiquitin-conjugating enzyme (E2 enzyme)

Identifiers

PMID30185618
PMCPMC6200922
OpenAlexW2890878422

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.