Evidence map›Paper›PMID 30185614›Full record

ReviewClinical science (London, England : 1979)2018

T follicular helper cell development and functionality in immune ageing.

Claire E Gustafson, Cornelia M Weyand, Jörg J Goronzy

Open access · greenAbstract readReview
In one paragraph

Review in Clinical science (London, England : 1979), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Review
  14. Vaccine-induced ICOSCell reports. Medicine · 2021
    Article
  15. Review
  16. Immunity to Influenza Infection in Humans.Cold Spring Harbor perspectives in medicine · 2021
    Review
  17. Review
  18. Article
  19. Article
  20. The Transcription Factor TCF1 in T Cell Differentiation and Aging.International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Claire E GustafsonDivision of Immunology and Rheumatology, Department of Medicine, Stanford University School of Medicine and the Department of Medicine, Veterans Administration Healthcare System, Palo Alto, CA, U.S.A.
Cornelia M WeyandDivision of Immunology and Rheumatology, Department of Medicine, Stanford University School of Medicine and the Department of Medicine, Veterans Administration Healthcare System, Palo Alto, CA, U.S.A.
Jörg J GoronzyDivision of Immunology and Rheumatology, Department of Medicine, Stanford University School of Medicine and the Department of Medicine, Veterans Administration Healthcare System, Palo Alto, CA, U.S.A. jgoronzy@stanford.edu.
VA Palo Alto Health Care System · US

Funding

VACCINE INDUCED IMMUNITY IN THE YOUNG AND AGEDU19AI057266 · NIAID · EMORY UNIVERSITY · PI Rafi Ahmed · 2003 to 2026
$81.7M
The Role of Inflammation in Cardiovascular DiseaseP01HL129941 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNSTEIN, KENNETH E · 2016 to 2020
$12.4M
The NOTCH Signaling Pathway in Large Vessel VasculitisR01HL117913 · NHLBI · STANFORD UNIVERSITY · PI WEYAND, CORNELIA M. · 2014 to 2025
$5.0M
Oligoclonal T Cell Expansion &Rheumatoid ArthritisR01AR042527 · NIAMS · STANFORD UNIVERSITY · PI WEYAND, CORNELIA M. · 1993 to 2022
$4.8M
microRNA Regulation of T Cell SenescenceR01AI108891 · NIAID · PALO ALTO VETERANS INSTIT FOR RESEARCH · PI GORONZY, JORG J · 2014 to 2023
$4.6M
Stanford Training Program in Aging ResearchT32AG047126 · NIA · STANFORD UNIVERSITY · PI VYJEYANTHI S PERIYAKOIL, TONY WYSS-CORAY · 2014 to 2026
$4.3M
Telomere Damage Responses and Immune AgingR01AI108906 · NIAID · STANFORD UNIVERSITY · PI WEYAND, CORNELIA M. · 2014 to 2024
$4.0M
Influence of Age on CD4 T Memory CellsR01AG045779 · NIA · PALO ALTO VETERANS INSTIT FOR RESEARCH · PI GORONZY, JORG J · 2013 to 2023
$4.0M
Memory T Cell Development and Survival in T Cell Responses of Older IndividualsR01AI129191 · NIAID · PALO ALTO VETERANS INSTIT FOR RESEARCH · PI GORONZY, JORG J · 2017 to 2021
$1.9M
T Cell Signaling in Rheumatoid ArthritisI01BX001669 · VA · VETERANS ADMIN PALO ALTO HEALTH CARE SYS · PI GORONZY, JORG J · 2012 to 2021
–
BLRD VA I01 BX001669NHLBI NIH HHS P01 HL129941NHLBI NIH HHS R01 HL117913NIAID NIH HHS R01 AI108891NIAID NIH HHS R01 AI108906NIAID NIH HHS R01 AI129191NIAID NIH HHS U19 AI057266NIAMS NIH HHS R01 AR042527NIA NIH HHS R01 AG045779NIA NIH HHS T32 AG047126
6 · The paper itself

Abstract

By 2050, there will be over 1.6 billion adults aged 65 years and older, making age-related diseases and conditions a growing public health concern. One of the leading causes of death in the ageing population is pathogenic infections (e.g. influenza,

Indexed as

AgingAntibodiesB-LymphocytesCommunicable DiseasesGerminal CenterHumansModels, ImmunologicalT-Lymphocytes, Helper-InducerVaccinesAntibodiesVaccinesB cell antibody productiongerminal centerImmunosenescenceT cell differentiationT follicular regulatory cellvaccine response

Identifiers

PMID30185614
PMCPMC6420344
OpenAlexW2890504652

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.