Evidence map›Paper›PMID 30185525›Full record

ArticleJournal of cell science2018

Chronic starvation induces noncanonical pro-death stress granules.

Lucas C Reineke, Shebna A Cheema, Julien Dubrulle, Joel R Neilson

Open access · greenAbstract read
In one paragraph

Article in Journal of cell science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 66 citations in OpenAlex.

  1. Article
  2. Comparative analysis of wavelength-specific UV stress granule formation.bioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Connecting the Dots: Stress Granule and Cardiovascular Diseases.Journal of cardiovascular translational research · 2025
    Review
  10. Review
  11. Article
  12. Stress Granule Induction in Rat Retinas Damaged by Constant LED Light.Investigative ophthalmology & visual science · 2025
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Lucas C ReinekeDepartment of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX 77030, USA lcreinek@bcm.edu neilson@bcm.edu.ORCID 0000-0002-8983-7696
Shebna A CheemaDepartment of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX 77030, USA.
Julien DubrulleIntegrated Microscopy Core, Baylor College of Medicine, Houston, TX 77030, USA.
Joel R NeilsonDepartment of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX 77030, USA lcreinek@bcm.edu neilson@bcm.edu.ORCID 0000-0002-3408-608X
Baylor College of Medicine · US

Funding

Tumor BiologyP30CA125123 · NCI · BAYLOR COLLEGE OF MEDICINE · PI DAVID R ROWLEY · 2007 to 2026
$73.9M
Translational control of EMT by the CELF1 RNA Binding ProteinR01CA190467 · NCI · BAYLOR COLLEGE OF MEDICINE · PI NEILSON, JOEL R · 2015 to 2021
$1.9M
BD Biosciences Special Order LSRIIS10RR024574 · NCRR · BAYLOR COLLEGE OF MEDICINE · PI LUMPKIN, ELLEN A · 2009 to 2009
$430k
Prospective Identification of Translational Regulators in EMTR21CA185769 · NCI · BAYLOR COLLEGE OF MEDICINE · PI NEILSON, JOEL R · 2015 to 2016
$379k
NCI NIH HHS P30 CA125123NCI NIH HHS R01 CA190467NCI NIH HHS R21 CA185769NCRR NIH HHS S10 RR024574
6 · The paper itself

Abstract

Stress granules (SGs) assemble under stress-induced conditions that inhibit protein synthesis, including phosphorylation of eIF2α, inhibition of the RNA helicase eIF4a proteins or inactivation of mTORC1. Classically defined SGs are composed of translation initiation factors, 40S ribosomes, RNA-binding proteins and poly(A)

Indexed as

ApoptosisAnimalsCell Line, TumorCytoplasmic GranulesEukaryotic Initiation Factor-2HumansKineticsMiceProtein BiosynthesisRibosomesEukaryotic Initiation Factor-2Cell deatheIF2αG3BP1StarvationStress granuleTranslation

Identifiers

PMID30185525
PMCPMC6198455
OpenAlexW2951237628

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.