Evidence map›Paper›PMID 30184178›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2019

Clinical and Epidemiologic Patterns of Chikungunya Virus Infection and Coincident Arboviral Disease in a School Cohort in Haiti, 2014-2015.

Jacob D Ball, Maha A Elbadry, Taina Telisma, Sarah K White, Sonese Chavannes, Marie Gina Anilis, Mattia Prosperi, Derek A T Cummings, John A Lednicky, J Glenn Morris and 1 more

Open access · hybridAbstract readHistorical Article
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 3 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 28 citations in OpenAlex.

  1. Pooled it
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  11. Journal of virology · 2023
    Article
  12. Analysis of Zika Virus Sequence Data Associated with a School Cohort in Haiti.The American journal of tropical medicine and hygiene · 2022
    Article
  13. Article
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  17. Review
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  19. Article
  20. Postnatally Acquired Zika Virus Disease Among Children, United States, 2016-2017.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Jacob D BallEmerging Pathogens Institute, College of Public Health and Health Professions and College of Medicine.
Maha A ElbadryEmerging Pathogens Institute, College of Public Health and Health Professions and College of Medicine.
Taina TelismaChristianville School Clinic, Christianville Foundation, Gressier, Haiti.
Sarah K WhiteEmerging Pathogens Institute, College of Public Health and Health Professions and College of Medicine.
Sonese ChavannesChristianville School Clinic, Christianville Foundation, Gressier, Haiti.
Marie Gina AnilisChristianville School Clinic, Christianville Foundation, Gressier, Haiti.
Mattia ProsperiEmerging Pathogens Institute, College of Public Health and Health Professions and College of Medicine.
Derek A T CummingsEmerging Pathogens Institute, College of Public Health and Health Professions and College of Medicine.
John A LednickyEmerging Pathogens Institute, College of Public Health and Health Professions and College of Medicine.
J Glenn MorrisEmerging Pathogens Institute, College of Public Health and Health Professions and College of Medicine.
Madsen Beau de RocharsEmerging Pathogens Institute, College of Public Health and Health Professions and College of Medicine.
University of Florida · USLiberal Arts University · RU

Funding

Recurrence of Cholera in Haiti: Exploration of Contributing Factors and Intervention StrategiesR01AI126357 · NIAID · UNIVERSITY OF FLORIDA · PI John Glenn Morris · 2016 to 2026
$7.3M
Models for synthesising molecular, clinical and epidemiological data, and translaU01GM110721 · NIGMS · IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE · PI CAUCHEMEZ, SIMON, FERGUSON, NEIL MORRIS · 2014 to 2018
$1.9M
NIAID NIH HHS R01 AI126357NIGMS NIH HHS U01 GM110721
6 · The paper itself

Abstract

backgroundBeginning in December 2013, an epidemic of chikungunya virus (CHIKV) infection spread across the Caribbean and into virtually all countries in the Western hemisphere, with >2.4 million cases reported through the end of 2017.

methodsWe monitored a cohort of school children in rural Haiti from May 2014, through February 2015, for occurrence of acute undifferentiated febrile illness, with clinical and laboratory data available for 252 illness episodes.

resultsOur findings document passage of the major CHIKV epidemic between May and July 2014, with 82 laboratory-confirmed cases. Subsequent peaks of febrile illness were found to incorporate smaller outbreaks of dengue virus serotypes 1 and 4 and Zika virus, with identification of additional infections with Mayaro virus, enterovirus D68, and coronavirus NL63. CHIKV and dengue virus serotype 1 infections were more common in older children, with a complaint of arthralgia serving as a significant predictor for infection with CHIKV (odds ratio, 16.2; 95% confidence interval, 8.0-34.4; positive predictive value, 66%; negative predictive value, 80%).

conclusionsViral/arboviral infections were characterized by a pattern of recurrent outbreaks and case clusters, with the CHIKV epidemic representing just one of several arboviral agents moving through the population. Although clinical presentations of these agents are similar, arthralgias are highly suggestive of CHIKV infection.

Indexed as

Chikungunya virusAdolescentArbovirus InfectionsChikungunya FeverChildChild, PreschoolCoinfectionDengue VirusDisease OutbreaksFemaleGeographyHaitiHistory, 21st CenturyHumansMalePublic Health Surveillancearboviruschikungunya virusHaiti

Identifiers

PMID30184178
PMCPMC6399436
OpenAlexW2889069426

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.