Trial reportBrazilian journal of cardiovascular surgery
Preventive Effect of Preoperative Vitamin D Supplementation on Postoperative Atrial Fibrillation.
Trial report in Brazilian journal of cardiovascular surgery. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 4 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- Role of vitamin D supplementation in prevention of new onset atrial fibrillation in post-coronary artery bypass graft patients in vitamin D deficient and insufficient populations: a systematic review and meta-analysis.BMC cardiovascular disorders · 2025Pooled it
- Role of vitamin D supplementation in modifying outcomes after surgery: a systematic review of randomised controlled trials.BMJ open · 2024Pooled it
- Association of Vitamin D or Calcium Supplementation with Cardiovascular Outcomes and Mortality: A Meta-Analysis with Trial Sequential Analysis.The journal of nutrition, health & aging · 2021Pooled it
- Association Between the Circulating Level of 25-Hydroxyvitamin D and Clinical Results After Cardiac Surgery: A Meta-Analysis and Systematic Review.Frontiers in cardiovascular medicine · 2021Pooled it
- Effects of high-dose vitamin D supplementation on the occurrence of post-operative atrial fibrillation after coronary artery bypass grafting: randomized controlled trial.General thoracic and cardiovascular surgery · 2020Trial
- Gut Microbiota, Microbial Metabolites, and Inflammation in Cardiac Surgery: Implications for Clinical Outcomes-A Narrative Review.Microorganisms · 2025Review
- Vitamin D supplementation among postoperative atrial fibrillation in patients undergoing coronary artery bypass grafting: a systematic review and meta-analysis.Annals of medicine and surgery (2012) · 2025Review
- Article
- Vitamin D and Cardiovascular Diseases: An Update.Cureus · 2023Review
- Recent Advances in Association Between Vitamin D Levels and Cardiovascular Disorders.Current hypertension reports · 2023Review
- Review
- The Possible Influence of Vitamin D Levels on the Development of Atrial Fibrillation-An Update.Nutrients · 2023Review
- Review
- Gut Microbiota in Patients with Postoperative Atrial Fibrillation Undergoing Off-Pump Coronary Bypass Graft Surgery.Journal of clinical medicine · 2023Article
- Predictive Value of QT Interval for Postoperative Atrial Fibrillation in Patients Undergoing Off-Pump Coronary Artery Bypass Surgery.Brazilian journal of cardiovascular surgery · 2022Article
- The Pathogenesis of Cardiac Arrhythmias in Vitamin D Deficiency.Biomedicines · 2022Review
- Post-Operative Atrial Fibrillation: Current Treatments and Etiologies for a Persistent Surgical Complication.Journal of surgery and research · 2022Article
- Review
- Is there any Link Between Vitamin D and Recurrence of Atrial Fibrillation after Cardioversion?Brazilian journal of cardiovascular surgery · 2020Article
- Is there any link between vitamin D deficiency and vasovagal syncope?Journal of arrhythmia · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo assess the relationship between preoperative vitamin D (vitD) supplementation and the development of postoperative atrial fibrillation (POAF).
methodsThe study group consisted of 328 consecutive patients. The ınfluence of preoperative vitD supplementation on POAF was reviewed in 136 patients who underwent coronary artery bypass graft surgery with vitD insufficiency (n=80) and vitD deficiency (n=56). Patients were assigned to receive either oral vitD (50.000 U) (treatment group, n=68) or not (control group, n=68) 48 hours before surgery. Patients were followed up during hospitalisation process with respect to POAF.
resultsThere was no significant difference between treatment and control groups with regards to age, gender, diabetes mellitus, smoking history, chronic obstructive pulmonary disease, left atrial diameter, and biochemical parameters. Also, there was no significant difference between these groups with regards to mean vitD level on both insufficiency and deficiency patients (24.6±3.7 vs. 24.9±3.9 ng/ml P=0.837, 11.4±4.9 vs. 10.9±5.2 ng/ml P=0.681, respectively). Although the occurrence of POAF was not significantly different among treatment and control groups in patients with vitD insufficiency (31% vs. 33% P=0.538), there was a significant difference between the two groups regarding to POAF in patients with vitD deficiency (18% vs. 29% P=0.02).
conclusionAlthough preoperative vitD supplementation was not found to be associated with prevention of POAF in patients with vitD insufficiency, it was found to be strongly associated with prevention of POAF in those with vitD deficiency.
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