Evidence map›Paper›PMID 30184028›Full record

Observational studyBrazilian journal of cardiovascular surgery

Predictors of Postoperative Acute Kidney Injury after Coronary Artery Bypass Graft Surgery.

Christian Ortega-Loubon, Manuel Fernández-Molina, Lucía Pañeda-Delgado, Pablo Jorge-Monjas, Yolanda Carrascal

Abstract readObservational Study
In one paragraph

Observational study in Brazilian journal of cardiovascular surgery. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  19. Risk factors for postoperative acute kidney injury after cardiac surgery.Archivos peruanos de cardiologia y cirugia cardiovascular
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Christian Ortega-LoubonDepartment of Cardiac Surgery, Clinic University Hospital of Valladolid, Valladolid, Spain.
Manuel Fernández-MolinaDepartment of Cardiac Surgery, Clinic University Hospital of Valladolid, Valladolid, Spain.
Lucía Pañeda-DelgadoDepartment of Cardiac Surgery, Clinic University Hospital of Valladolid, Valladolid, Spain.
Pablo Jorge-MonjasDepartment of Anesthesia, Clinic University Hospital of Valladolid, Valladolid, Spain.
Yolanda CarrascalDepartment of Cardiac Surgery, Clinic University Hospital of Valladolid, Valladolid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aims of this study were to identify the risk factors associated with acute kidney injury (AKI) after isolated surgical revascularization with cardiopulmonary bypass and to develop a model to predict the appearance of postoperative AKI.

methodsA total of 435 adult patients who underwent primary isolated coronary artery bypass graft (CABG) surgery, from 2012 to 2016, in the Clinic University Hospital of Valladolid (Spain) were enrolled. AKI was defined according to the risk, injury, failure, loss, and end-stage (RIFLE) criteria. Data were collected from hospital electronic medical records. Multiple logistic regression analysis was used to identify risk factors.

resultsThe prevalence of AKI was 12.4%. Multivariate analysis identified age (odds ratio [OR], 1.056; 95% confidence interval [CI], 1.016-1.098; P=0.005), hypertension (OR, 3.078; 95% CI, 1.151-8.230; P=0.018), low ejection fraction (EF) (OR, 6.785; 95% CI, 2.080-22.135; P=0.001), estimated glomerular filtration rate (eGFR) (OR, 1.017; 95% CI, 1.005-1.028; P=0.014), EuroSCORE II (OR, 1.049; 95% CI, 1.004-1.096; P=0.033), and no intake of calcium-channel blockers (CCB) (OR, 4.892; 95% CI, 1.496-16.025; P=0.022) as risk factors for AKI. These risk factors were included in a model to predict postoperative AKI with an area under a receiver operating characteristic curve of 0.783±0.036 (95% CI, 0.713-0.854; P<0.0001).

conclusionAge, hypertension, low EF, eGFR, EuroSCORE II, and no intake of CCB were independent risk factors for postoperative AKI. These factors provide an easy and accurate model to predict postoperative AKI in patients undergoing cardiac surgery.

Indexed as

Acute Kidney InjuryAgedAge FactorsCardiopulmonary BypassCoronary Artery BypassFemaleGlomerular Filtration RateHumansLogistic ModelsMaleMiddle AgedPostoperative ComplicationsPredictive Value of TestsReference ValuesRetrospective StudiesRisk Assessment

Identifiers

PMID30184028
PMCPMC6122763

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.