Evidence map›Paper›PMID 30183746›Full record

ArticlePloS one2018

Knowledge, perceptions and confidence of physicians and pharmacists towards pharmacogenetics practice in Kuwait.

Abdullah Albassam, Shahad Alshammari, Ghadeer Ouda, Samuel Koshy, Abdelmoneim Awad

Erratum issuedAbstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed.

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  11. Critical Care Nurses' Knowledge on Prevention of Ventilator-associated Pneumonia: A Cross-sectional Study.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024
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  12. Circulation · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Abdullah AlbassamDepartment of Pharmacy Practice, Faculty of Pharmacy, Kuwait University, Kuwait City, Kuwait.ORCID 0000-0001-6698-5947
Shahad AlshammariDepartment of Pharmacy, Jahra Hospital, Ministry of Health, Jahra City, Kuwait.
Ghadeer OudaDrug Inspection Administration, Ministry of Health, Kuwait City, Kuwait.
Samuel KoshyDepartment of Pharmacy Practice, Faculty of Pharmacy, Kuwait University, Kuwait City, Kuwait.
Abdelmoneim AwadDepartment of Pharmacy Practice, Faculty of Pharmacy, Kuwait University, Kuwait City, Kuwait.ORCID 0000-0002-2266-3687

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPharmacogenetics practice has been successfully implemented in many developed countries to enhance personalized medicine and improve clinical and economic outcomes. An understanding of healthcare providers' knowledge, perceptions, confidence towards pharmacogenetics, and their active enrollment with pharmacogenetic testing is essential for test acceptance and utilization. This study was designed to assess physicians' and pharmacists' knowledge, perceptions, and confidence towards pharmacogenetics, determine the preferred learning format for their future education in pharmacogenetics, and identify the barriers to its application in their practice settings.

methodsA cross-sectional survey was conducted using a pretested self-administered questionnaire on a sample of 629 randomly selected physicians and pharmacists. Descriptive and comparative analyses were used in data analysis.

resultsThe response rate was 98.1%. Less than one-tenth of respondents were exposed to pharmacogenetics education or training (8.9%), applied pharmacogenetics testing in their practice (9.4%), or provided patient counselling on the results of the pharmacogenetic testing (9.1%), and over 90% of them were physicians. The overall respondents' mean (SD) total knowledge score percentage was low [45.0% (24)] and there was no significant difference between the physicians and pharmacists scores (p>0.05). Only 16.0% of participants indicated that they felt confident in applying pharmacogenetics in their practice settings. Despite these low levels of knowledge and self-confidence, 70.2% of participants expressed overall positive perceptions towards pharmacogenetics and its clinical implications. These positive overall perceptions were found to be significantly more common among pharmacists compared to physicians (p<0.05). The top two perceived barriers facing the implementation of pharmacogenetics in Kuwait were lack of education or training and clinical guidelines.

conclusionsThese findings highlight important concerns and will aid in the assessment of current pharmacogenetics practice. Also, they will provide further insight in designing future targeted multifaceted interventions to promote the adoption and utilization of pharmacogenetics testing in Kuwait.

Indexed as

Attitude of Health PersonnelHealth Knowledge, Attitudes, PracticePharmacogeneticsAdultCross-Sectional StudiesFemaleGenetic TestingHumansKuwaitMalePharmacistsPhysiciansPrecision Medicine

Identifiers

PMID30183746
PMCPMC6124749

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.