Evidence map›Paper›PMID 30183718›Full record

Trial reportPloS one2018

Barriers to supportive care during the Ebola virus disease outbreak in West Africa: Results of a qualitative study.

Christine Loignon, Elysée Nouvet, François Couturier, Lynda Benhadj, Neill K J Adhikari, Srinivas Murthy, Rob A Fowler, François Lamontagne

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Christine LoignonFaculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Canada.ORCID 0000-0002-9828-3090
Elysée NouvetSchool of Health Studies, University of Western Ontario, London, Canada.
François CouturierFaculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Canada.
Lynda BenhadjFaculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Canada.
Neill K J AdhikariDepartment of Critical Care Medicine, Sunnybrook Health Sciences Centre, Interdepartmental Division of Critical Care, University of Toronto, Toronto, Canada.ORCID 0000-0003-4038-5382
Srinivas MurthyFaculty of Medicine, University of British Columbia, Vancouver, Canada.
Rob A FowlerDepartment of Critical Care Medicine, Sunnybrook Health Sciences Centre, Interdepartmental Division of Critical Care, University of Toronto, Toronto, Canada.
François LamontagneFaculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Canada.ORCID 0000-0002-0360-3427
Université de Sherbrooke · CASunnybrook Health Science Centre · CAUniversity of British Columbia · CAWestern University · CA

Funding

Canadian Institutes of Health Research 143490
6 · The paper itself

Abstract

backgroundDuring the 2013-2016 West Africa Ebola outbreak, supportive care was the only non-experimental treatment option for patients with Ebola virus disease (EVD). However, providing care that would otherwise be routine for most clinical settings in the context of a highly contagious and lethal pathogen is much more challenging. The objective of this study was to document and deepen understanding of barriers to provision of supportive care in Ebola treatment units (ETUs) as perceived by those involved in care delivery during the outbreak.

methodsThis qualitative study consisted of 29 in-depth semi-structured interviews with stakeholders (decision-makers, physicians, nurses) involved in patient care delivery during the outbreak. Analysis consisted of interview debriefing and team-based transcript coding in NVivo10 software using thematic analysis.

findingsParticipants emphasized three interconnected barriers to providing high-quality supportive care during the outbreak: 1) lack of material and human resources in ETUs; 2) ETU organizational structure limiting the provision of supportive clinical care; and 3) delayed and poorly coordinated policies limiting the effectiveness of global and national responses. Participants also noted the ethical complexities of defining and enacting best clinical practices in low-income countries. They noted tension between, on one hand, scaling up minimal care and investing in clinical care preparedness to a level sustainable in West Africa and, on the other, providing a higher level of supportive care, which in low-resource health systems would require important investments.

conclusionOur findings identified potentially modifiable barriers to the delivery of supportive care to patients with EVD in West Africa. Addressing these in the inter-outbreak period will be useful to improve patient care and outcomes during inevitable future outbreaks. Promoting community trust and engagement through long-term capacity building of the healthcare workforce and infrastructure would increase both health system resilience and ability to handle other outbreaks of emerging diseases.

Indexed as

Delivery of Health CareDisease OutbreaksEbolavirusAfrica, WesternFemaleHemorrhagic Fever, EbolaHumansMale

Identifiers

PMID30183718
PMCPMC6124726
OpenAlexW2889870391

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.