ArticleeLife2018
Timing of the reticular lamina and basilar membrane vibration in living gerbil cochleae.
Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.
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Who cites it
60 citing papers in PubMed.
- Broadband amplification of organ of Corti vibrations in the mouse cochlear apex.bioRxiv : the preprint server for biology · 2026Article
- Active deformation in the basal organ of Corti in gerbil.Biophysical journal · 2026Article
- Distinctive mechanical response characteristics of the guinea pig apical cochlear organ of Corti and basilar membrane.The Journal of general physiology · 2026Article
- An alternative pathway for delivery of power by outer hair cells to cochlear traveling waves.Hearing research · 2026Article
- Study of organ of Corti motion in the guinea pig base including differential analysis of internal motion.Hearing research · 2025Article
- Suppression of Low-Frequency Tones in the Organ of Corti Vibrations of the Basal Turn in the Mongolian Gerbil Cochlea.Journal of the Association for Research in Otolaryngology : JARO · 2025Article
- The impulse response of the organ of Corti at the apex of the intact cochlea.Scientific reports · 2025Article
- Low-side and multitone suppression in the base of the gerbil cochlea.Biophysical journal · 2025Article
- Outer hair cells stir cochlear fluids.eLife · 2025Article
- Corti Fluid Is a Medium for Outer Hair Cell Force Transmission.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Visualizing motions within the cochlea's organ of Corti and illuminating cochlear mechanics with optical coherence tomography.Hearing research · 2025Review
- Evaluating the Correlation Between Stimulus Frequency Otoacoustic Emission Group Delays and Tuning Sharpness in a Cochlear Model.Journal of the Association for Research in Otolaryngology : JARO · 2024Article
- Tuning and Timing of Organ of Corti Vibrations at the Apex of the Intact Chinchilla Cochlea.Journal of the Association for Research in Otolaryngology : JARO · 2024Article
- Outer hair cells stir cochlear fluids.bioRxiv : the preprint server for biology · 2024Article
- Article
- Asymmetric vibrations in the organ of Corti by outer hair cells measured from excised gerbil cochlea.Communications biology · 2024Article
- Regional differences in cochlear nonlinearity across the basal organ of Corti of gerbil: Regional differences in cochlear nonlinearity.Hearing research · 2024Article
- Advective mass transport along the cochlear coil.AIP conference proceedings · 2024Article
- Optogenetics Reveals Roles for Supporting Cells in Force Transmission to and From Outer Hair Cells in the Mouse Cochlea.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Intracochlear overdrive: Characterizing nonlinear wave amplification in the mouse apex.The Journal of the Acoustical Society of America · 2023Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Auditory sensory outer hair cells are thought to amplify sound-induced basilar membrane vibration through a feedback mechanism to enhance hearing sensitivity. For optimal amplification, the outer hair cell-generated force must act on the basilar membrane at an appropriate time at every cycle. However, the temporal relationship between the outer hair cell-driven reticular lamina vibration and the basilar membrane vibration remains unclear. By measuring sub-nanometer vibrations directly from outer hair cells using a custom-built heterodyne low-coherence interferometer, we demonstrate in living gerbil cochleae that the reticular lamina vibration occurs after, not before, the basilar membrane vibration. Both tone- and click-induced responses indicate that the reticular lamina and basilar membrane vibrate in opposite directions at the cochlear base and they oscillate in phase near the best-frequency location. Our results suggest that outer hair cells enhance hearing sensitivity through a global hydromechanical mechanism, rather than through a local mechanical feedback as commonly supposed.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.