Evidence map›Paper›PMID 30183556›Full record

ArticleThe journal of spinal cord medicine2021

Multimorbidity of overweight and obesity alongside anxiety and depressive disorders in individuals with spinal cord injury.

Scott Graupensperger, Shane N Sweet, M Blair Evans

Abstract read
In one paragraph

Article in The journal of spinal cord medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Scott GraupenspergerDepartment of Kinesiology, Pennsylvania State University, State College, Pennsylvania, USA.ORCID 0000-0002-8655-1190
Shane N SweetDepartment of Kinesiology & Physical Education, McGill University, Montreal, Quebec, Canada.ORCID 0000-0002-6172-3769
M Blair EvansDepartment of Kinesiology, Pennsylvania State University, State College, Pennsylvania, USA.ORCID 0000-0003-0668-4928

Funding

Penn State Clinical and Translational Science InstituteUL1TR002014 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI KRASCHNEWSKI, JENNIFER L. · 2016 to 2025
$33.7M
NRSA Training CoreTL1TR002016 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI THOMAS, GAIL D. · 2016 to 2025
$3.4M
NCATS NIH HHS TL1 TR002016NCATS NIH HHS UL1 TR002014
6 · The paper itself

Abstract

objectiveTo compare the prevalence of anxiety/depression and overweight/obesity (Aim 1) and the multimorbidity of these conditions (Aim 2) in a sample of adults with and without spinal cord injury (SCI). Aim 3 was to examine whether overweight/obese individuals with SCI differ on the prevalence of anxiety/depressive disorders compared to non-overweight/obese individuals with SCI.

designRetrospective cohort study.

participantsIndividuals ≥16 years old who had patient encounters between January 1, 2011, and February 28, 2018. In total, 761 598 individuals were included, of which 3136 had SCI.

main outcome measuresIndividuals were identified as diagnosed with SCI, anxiety and/or depressive disorders, and overweight/obesity using the International Classification of Diseases.

resultsAge-adjusted odds ratios (ORs) were calculated using logistic regression. In contrast to non-SCI individuals, those with SCI had increased odds of anxiety disorders (OR: 3.58, 95% CI [3.29-3.90]), depressive disorders (OR: 4.33, 95% CI [3.95-4.74]), and overweight/obesity (OR: 3.08, 95% CI [2.80-3.38]). Pertaining to multimorbidity, individuals with SCI had increased odds of having overweight/obesity alongside anxiety disorders (OR: 4.30, 95% CI [3.71-4.98]) and overweight/obesity alongside depressive disorders (OR: 4.69, 95% CI [4.01-5.47]) compared to those without SCI. Individuals with SCI who were diagnosed as overweight/obese had increased odds of having anxiety disorders (OR: 2.54, 95% CI [2.06-3.13]), and depressive disorders (OR: 2.70, 95% CI [2.18-3.36]), relative to non-overweight/obese individuals with SCI.

conclusionsThis work is among the first to find evidence that individuals with SCI are at heightened odds of overweight/obesity alongside anxiety and/or depressive disorders. This early work holds clinical implications for treating these interrelated comorbidities in SCI.

Indexed as

Depressive DisorderSpinal Cord InjuriesAdolescentAdultAnxietyAnxiety DisordersHumansMultimorbidityObesityOverweightRetrospective StudiesMental healthMultimorbidityPhysical disabilityWeight gain

Identifiers

PMID30183556
PMCPMC8725715

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.