Evidence map›Paper›PMID 30183373›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2019

Plasma glycomics predict cardiovascular disease in patients with ART-controlled HIV infections.

Douglas M Oswald, Edward S Sim, Courtney Baker, Obada Farhan, Sara M Debanne, Nathan J Morris, Benigno G Rodriguez, Mark B Jones, Brian A Cobb

Open access · bronzeAbstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Glycosylation and Cardiovascular Diseases.Advances in experimental medicine and biology · 2021
    Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Douglas M OswaldDepartment of Pathology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Edward S SimDepartment of Pathology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Courtney BakerDepartment of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Obada FarhanDepartment of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Sara M DebanneDepartment of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Nathan J MorrisDepartment of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Benigno G RodriguezDivision of Infectious Diseases and HIV Medicine, Department of Medicine, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.
Mark B JonesDepartment of Pathology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Brian A CobbDepartment of Pathology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Case Western Reserve University · USUniversity School · USUniversity Hospitals of Cleveland · US

Funding

WG3: HIV, Co-infections and Co-morbiditiesP30AI036219 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI Alan David Levine · 1994 to 2026
$50.0M
Regulatory Mechanisms of Glycoprotein SialylationR01GM115234 · NIGMS · CASE WESTERN RESERVE UNIVERSITY · PI Brian A Cobb · 2016 to 2026
$5.1M
Immunology Training Program-PredoctoralT32AI089474 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI COBB, BRIAN A · 2010 to 2025
$3.4M
Antigenic Carbohydrate Structure, Function, and SpecificityR01GM082916 · NIGMS · CASE WESTERN RESERVE UNIVERSITY · PI COBB, BRIAN A · 2009 to 2016
$1.9M
NIAID NIH HHS P30 AI036219NIAID NIH HHS T32 AI089474NIGMS NIH HHS R01 GM082916NIGMS NIH HHS R01 GM115234
6 · The paper itself

Abstract

Despite effective control of HIV infection with antiretroviral drugs, individuals with HIV have high incidences of secondary diseases. These sequelae, such as cardiovascular disease (CVD), are poorly understood and represent a major health burden. To date, predictive biomarkers of HIV-associated secondary disease have been elusive, making preventative clinical management essentially impossible. Here, we applied a newly developed and easy to deploy, multitarget, and high-throughput glycomic analysis to banked HIV

Indexed as

GlycomicsAdultAntiviral AgentsBiomarkersCarbohydratesCardiovascular DiseasesFemaleGlycosylationHIV InfectionsHumansLogistic ModelsMaleMiddle AgedProof of Concept StudyAntiviral AgentsBiomarkersCarbohydratesbiomarkerCVDglycanglycomelectin

Identifiers

PMID30183373
PMCPMC6338643
OpenAlexW2891331901

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.