Evidence map›Paper›PMID 30183322›Full record

ArticleAmerican journal of physiology. Cell physiology2018

Mixing and delivery of multiple controlled oxygen environments to a single multiwell culture plate.

Ming Yao, Tyler Sattler, Zahid N Rabbani, Thomas Pulliam, Glenn Walker, Michael P Gamcsik

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Cell physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. CORP: Sources and degrees of variability in whole animal intermittent hypoxia experiments.Journal of applied physiology (Bethesda, Md. : 1985) · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ming YaoDepartment of Mechanical and Aerospace Engineering, North Carolina State University , Raleigh, North Carolina.
Tyler SattlerUniversity of North Carolina/North Carolina State University Joint Department of Biomedical Engineering, North Carolina State University , Raleigh, North Carolina.
Zahid N RabbaniUniversity of North Carolina/North Carolina State University Joint Department of Biomedical Engineering, North Carolina State University , Raleigh, North Carolina.
Thomas PulliamDepartment of Chemical and Biomolecular Engineering, North Carolina State University , Raleigh, North Carolina.
Glenn WalkerUniversity of North Carolina/North Carolina State University Joint Department of Biomedical Engineering, North Carolina State University , Raleigh, North Carolina.
Michael P GamcsikUniversity of North Carolina/North Carolina State University Joint Department of Biomedical Engineering, North Carolina State University , Raleigh, North Carolina.ORCID 0000-0002-0676-0110
North Carolina State University · US

Funding

High-Throughput Screening Under Static or Dynamic HypoxiaR21CA202804 · NCI · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI GAMCSIK, MICHAEL · 2016 to 2018
$574k
NCI NIH HHS R21 CA202804
6 · The paper itself

Abstract

Precise oxygen control is critical to evaluating cell growth, molecular content, and stress response in cultured cells. We have designed, fabricated, and characterized a 96-well plate-based device that is capable of delivering eight static or dynamically changing oxygen environments to different rows on a single plate. The device incorporates a gas-mixing tree that combines two input gases to generate the eight gas mixtures that supply each row of the plate with a different gas atmosphere via a removable manifold. Using air and nitrogen as feed gases, a single 96-well plate can culture cells in applied gas atmospheres with Po

Indexed as

Caco-2 CellsCell Culture TechniquesCell HypoxiaCell ProliferationHumansHypoxia-Inducible Factor 1, alpha SubunitMCF-7 CellsOxygenHypoxia-Inducible Factor 1, alpha SubunitOxygencell culturecycling hypoxiafinite element analysisoxygen diffusionpermeability

Identifiers

PMID30183322
PMCPMC6293053
OpenAlexW2889659286

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.