ArticleAnnals of surgical treatment and research2018
Postcholecystectomy syndrome: symptom clusters after laparoscopic cholecystectomy.
Article in Annals of surgical treatment and research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Postcholecystectomy diarrhoea rate and predictive factors: a systematic review of the literature.BMJ open · 2022Pooled it
- Clinical perspectives on post-cholecystectomy syndrome: a narrative review.Annals of medicine · 2025Review
- Analysis of the incidence of post-cholecystectomy diarrhea and its influencing factors in Hainan Province.BMC gastroenterology · 2025Article
- Article
- The causal relationship between diet habits and cholelithiasis: a comprehensive Mendelian randomization (MR) study.Frontiers in nutrition · 2024Article
- Successful treatment of cholecystolithiasis by ERCP: A case report and literature review (with video).Journal of digestive diseases · 2022Review
- Elevated Levels of PGE2-Metabolite in Cerebrospinal Fluid and Cox-2 Gene Polymorphisms in Patients with Chronic, Post Cholecystectomy Pain and Visceral Hyperalgesia Compared to Healthy Controls. A Hypothesis-Generating Pilot Study.Journal of pain research · 2022Article
- Rates of Bile Acid Diarrhoea After Cholecystectomy: A Multicentre Audit.World journal of surgery · 2021Article
- Efficacy and safety of endoscopic laser lithotripsy and lithotomy through the lumen-apposing metal stent for giant gallbladder stones.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2020Article
- Acupuncture for the Postcholecystectomy Syndrome: A Systematic Review and Meta-Analysis.Evidence-based complementary and alternative medicine : eCAM · 2020Review
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePostcholecystectomy syndrome (PCS) is characterized by abdominal symptoms following gallbladder removal. However, there is no consensus for the definition or treatment for PCS. The purpose of this study was to define PCS among various symptoms after laparoscopic cholecystectomy, and to identify risk factors affecting PCS.
methodsThis study was conducted at Dongguk University Ilsan Hospital and Chung-Ang University Hospital (2012-2013). Outcomes were assessed using European Organization for Research and Treatment of Cancer QLQ-C30 questionnaire. Symptom cluster for determining PCS was made by factor analysis. Cluster analysis evaluating risk factors of PCS was made by Ward methods and Dentogram.
resultsFactor analysis revealed three distinct symptom clusters, those are 'insomnia and financial difficulties (eigenvalue, 1.707; Cronbach α, 0.190),' 'appetite loss and constipation (eigenvalue, 1.413; Cronbach α, 0.480),' and 'right upper quadrant (RUQ) pain and diarrhea (eigenvalue, 1.245; Cronbach α, 0.315).' Among these symptom clusters, the cluster of 'RUQ pain and diarrhea' was determined as PCS. However, we could not find any risk factors between high symptomatic group and low symptomatic group.
conclusionPCS could consist of RUQ pain and diarrhea. Well-designed prospective trials are needed to determine risk factors of PCS.
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Registered trials
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