Evidence map›Paper›PMID 30181952›Full record

ArticleEpilepsy & behavior case reports2018

Auras localized to the temporal lobe disrupt verbal memory and learning - Causal evidence from direct electrical stimulation of the hippocampus.

Diana Pizarro, Emilia Toth, Auriana Irannejad, Kristen O Riley, Zeenat Jaisani, Wolfgang Muhlhofer, Roy Martin, Sandipan Pati

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Epilepsy & behavior case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Diana PizarroDepartment of Neurology, University of Alabama at Birmingham, AL, United States of America.
Emilia TothDepartment of Neurology, University of Alabama at Birmingham, AL, United States of America.
Auriana IrannejadEpilepsy and Cognitive Neurophysiology Laboratory, University of Alabama at Birmingham, AL, United States of America.
Kristen O RileyDepartment of Neurosurgery, University of Alabama at Birmingham, AL, United States of America.
Zeenat JaisaniDepartment of Neurology, University of Alabama at Birmingham, AL, United States of America.
Wolfgang MuhlhoferDepartment of Neurology, University of Alabama at Birmingham, AL, United States of America.
Roy MartinDepartment of Neurology, University of Alabama at Birmingham, AL, United States of America.
Sandipan PatiDepartment of Neurology, University of Alabama at Birmingham, AL, United States of America.
University of Alabama at Birmingham · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Auras (focal aware seizure; FAS) are subjective ictal events with retained consciousness. Epileptiform activities can disrupt cognitive tasks, but studies are limited to seizures with impaired awareness. As a proof of concept, we examined the cognitive effects of direct electrical stimulation to the left hippocampus which induced a habitual FAS in a patient with left mesial temporal lobe epilepsy. During the induced habitual FAS, verbal memory performance declined significantly as compared to pre-stimulation testing. Tasks measuring auditory working memory and psychomotor processing speed were not affected by the stimulation. The study confirms that FAS can impair episodic verbal memory and learning.

Indexed as

AuraEpilepsyFocal aware seizureHippocampusLearningVerbal memory

Identifiers

PMID30181952
PMCPMC6120344
OpenAlexW2887579315

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.