ArticleActa radiologica open2018
Reliability of virtual non-contrast computed tomography angiography: comparing it with the real deal.
Article in Acta radiologica open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A meta-analysis of the diagnostic accuracy of dual-energy computed tomography for endoleak detection after endovascular aneurysm repair.European radiology · 2025Pooled it
- Imaging review of aortic fistulas.Abdominal radiology (New York) · 2026Review
- Virtual non-contrast images from dual-layer spectral CT: comparison with true non-contrast across abdominal structures.European radiology · 2026Article
- Spectral Computed Tomography Angiography in Visceral Artery Aneurysms: Technical Principles and Clinical Applications.Tomography (Ann Arbor, Mich.) · 2026Review
- Virtual Non-Contrast Reconstructions Derived from Dual-Energy CTA Scans in Peripheral Arterial Disease: Comparison with True Non-Contrast Images and Impact on Radiation Dose.Journal of clinical medicine · 2025Article
- Assessing anemia in stroke patients through virtual non-contrast imaging with photon-counting detector CT: validation on supra-aortic vessel CT-Angiography.Neuroradiology · 2025Article
- Atherosclerotic Abdominal Aortic Aneurysms on Computed Tomography Angiography: A Narrative Review on Spectrum of Findings, Structured Reporting, Treatment, Secondary Complications and Differential Diagnosis.Diagnostics (Basel, Switzerland) · 2025Review
- Evaluation of virtual non-contrast detector-based spectral CT images in comparison to true unenhanced images in 20 rabbits.Frontiers in veterinary science · 2025Article
- Dual-Energy and Photon-Counting Computed Tomography in Vascular Applications-Technical Background and Post-Processing Techniques.Diagnostics (Basel, Switzerland) · 2024Review
- Virtual Non-Contrast versus True Native in Photon-Counting CT: Stability of Density of Upper Abdominal Organs and Vessels.Diagnostics (Basel, Switzerland) · 2024Article
- Dual-Energy CT in Oncologic Imaging.Tomography (Ann Arbor, Mich.) · 2024Review
- Review of Clinical Applications of Dual-Energy CT in Patients after Endovascular Aortic Repair.Journal of clinical medicine · 2023Review
- Dual-layer spectral computed tomography aortography using a seventy-five-percent-reduced iodine dose protocol and multiparameter spectral imaging: comparison with conventional computed tomography imaging.Quantitative imaging in medicine and surgery · 2023Article
- Dual-Energy Computed Tomography in Stroke Imaging : Value of a New Image Acquisition Technique for Ischemia Detection after Mechanical Thrombectomy.Clinical neuroradiology · 2023Article
- Detection of Low Blood Hemoglobin Levels on Pulmonary CT Angiography: A Feasibility Study Combining Dual-Energy CT and Machine Learning.Tomography (Ann Arbor, Mich.) · 2023Article
- Dual Source Photon-Counting Computed Tomography-Part II: Clinical Overview of Neurovascular Applications.Journal of clinical medicine · 2023Review
- Virtual non-contrast images from dual-energy CT angiography of the abdominal aorta and femoral arteries: comparison with true non-contrast CT images.The British journal of radiology · 2022Article
- Virtual Non-Contrast Reconstructions of Photon-Counting Detector CT Angiography Datasets as Substitutes for True Non-Contrast Acquisitions in Patients after EVAR-Performance of a Novel Calcium-Preserving Reconstruction Algorithm.Diagnostics (Basel, Switzerland) · 2022Article
- Comparative study of true and virtual non-contrast imaging generated from dual-layer spectral CT in patients with upper aerodigestive tract cancer.Polish journal of radiology · 2022Article
- Quantitative benchmarking of iodine imaging for two CT spectral imaging technologies: a phantom study.European radiology experimental · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundComputed tomographic angiography (CTA) may require a non-contrast enhanced dataset for the diagnostic workup. By using dual-energy acquisition, it is possible to obtain a virtual non-contrast-enhanced (VNC) dataset, thereby possibly eliminating the non-contrast acquisition and reducing the radiation dose. PURPOSE: To compare image quality of VNC images reconstructed from arterial phase dual-energy CTA to true non-contrast (TNC) images, and to assess whether VNC images were of sufficient quality to replace TNC images. MATERIAL AND
methodsThirty consecutive patients with suspected abdominal aortic aneurysm, aortic dissection, or subacute control after EVAR/TEVAR were examined with dual-energy CT (DECT). The examination protocol included a single-energy TNC, DECT arterial phase (80 kV/Sn140 kV), and single-energy in venous phase of the aorta. A VNC dataset was obtained from the DE acquisition from arterial phase scans. Mean attenuation and image noise were measured within regions of interest at three levels in the aorta in TNC and VNC images. Comparison of the TNC and VNC images for artefacts was made side-by-side. Subjective evaluation included overall image quality on a 4-grade scale, and quantitative analysis of algorithm-induced artefacts by two experienced readers.
resultsFor all cases, the aortic attenuation was significantly higher at VNC than at TNC. Image noise measured quantitatively was also significantly higher at VNC than at TNC. Subjective image quality was lower for VNC (mean = 3.1 for VNC, 3.7 = for TNC) but there were no cases rated non-diagnostic.
conclusionVNC images based on arterial phase CTA have significantly higher mean attenuation and higher noise levels compared to TNC.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.