ReviewAnnals of medicine and surgery (2012)2018
Post hepatectomy liver failure - A comprehensive review of current concepts and controversies.
Review in Annals of medicine and surgery (2012), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
54 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Systematic review on peri-operative lactate measurements to predict outcomes in patients undergoing liver resection.Journal of hepato-biliary-pancreatic sciences · 2020Pooled it
- Markers of liver regeneration-the role of growth factors and cytokines: a systematic review.BMC surgery · 2020Pooled it
- Influence of Probiotics Administration Before Liver Resection in Patients with Liver Disease: A Randomized Controlled Trial.World journal of surgery · 2022Trial
- Prediction of post-hepatectomy liver failure risk in patients with colorectal cancer liver metastases utilizing gadoxetic acid-enhanced MRI radiomics with automatic segmentation and image registration.Abdominal radiology (New York) · 2026Article
- Effect of dual hepatic and portal vein embolization on future liver remnant function and volume prior to major hepatectomy.Annals of hepato-biliary-pancreatic surgery · 2026Article
- Nanomaterials: An innovative integrative paradigm for hepatocellular carcinoma adjuvant treatment.Asian journal of pharmaceutical sciences · 2026Review
- Preoperative Albumin-Bilirubin Score as a Predictor of Postoperative Complications After Liver Resection.Cureus · 2026Article
- Serum antithrombin III as an early predictive marker for post-hepatectomy liver failure: a prospective cohort study.Scientific reports · 2026Article
- Daily increment of residual liver regeneration (DIRER) predicts tumor recurrence and mortality after radical hepatectomy for hepatocellular carcinoma.Journal of gastrointestinal oncology · 2026Article
- Article
- Liver hypertrophy post-Yttrium-90 versus portal vein embolization: A systematic review and meta-analysis.Annals of hepato-biliary-pancreatic surgery · 2026Article
- Liver microbial DNA signatures and extracellular vesicle epitopes as predictors of post-hepatectomy liver failure.iScience · 2025Article
- Intracellular CIRP promotes liver regeneration via STAT3 signaling pathway activation after partial hepatectomy in mice.International journal of molecular medicine · 2025Article
- Predicting liver function after hemihepatectomy in patients with hepatocellular carcinoma using different modalities.World journal of clinical oncology · 2024Article
- Enhanced recovery after liver surgery in cirrhotic patients: a systematic review and meta-analysis.Perioperative medicine (London, England) · 2024Article
- A small molecule MST1/2 inhibitor accelerates murine liver regeneration with improved survival in models of steatohepatitis.PNAS nexus · 2024Article
- RoboticHeliyon · 2024Article
- Hepatocellular Carcinoma: The Role of Surgery in Liver Cirrhosis.Visceral medicine · 2024Review
- Article
- Prevalence and clinical relevance of liver dysfunction after thoracic surgery: a retrospective study.Scientific reports · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Post hepatectomy liver failure (PHLF) comprises of a conundrum of symptoms and signs following major hepatic resections. The pathophysiology essentially revolves around disruption of the normal hepatocyte regeneration and disturbed liver homeostasis. Prompt identification of the pre-operative predictors of PHLF in the form of biochemical parameters and imaging features are of paramount importance for any hepatic surgeon and forms the cornerstone of its management. Treatment revolves around a goal-directed resuscitation of the systemic organ failure. Auxiliary support systems such as liver dialysis devices and stem cell therapy are still under investigational trials for treatment of the same. Orthotopic liver transplantation (OLT) is the last resort in most cases not responding to other measures.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.