Evidence map›Paper›PMID 30181750›Full record

ArticleJournal of research in medical sciences : the official journal of Isfahan University of Medical Sciences2018

Chemotherapy-related infectious complications in patients with Hematologic malignancies.

Raluca-Ana Rusu, Dana Sîrbu, Daniela Curşeu, Bogdana Năsui, Mădălina Sava, Ştefan Cristian Vesa, Anca Bojan, Cosmin Lisencu, Monica Popa

Open access · goldAbstract read
In one paragraph

Article in Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.5field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Infections in Hospitalized Cancer Patients.World journal of oncology · 2021
    Review
  7. Article
  8. Article
  9. The application of clinical genetics · 2021
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Raluca-Ana RusuIuliu Haţieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Dana SîrbuDepartment of Hygiene, Iuliu Haţieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Daniela CurşeuDepartment of Hygiene, Iuliu Haţieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Bogdana NăsuiDepartment of Hygiene, Iuliu Haţieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Mădălina SavaDepartment of Dermatology, University of Oradea, Oradea, Romania.
Ştefan Cristian VesaDepartment of Pharmacology, Toxicology and Clinical Pharmacology, Iuliu Haţieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Anca BojanDepartment of Hematology, Iuliu Ha-ieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Cosmin LisencuDepartment of Oncologic Surgery and Oncologic Gynecology, Iuliu Haţieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Monica PopaDepartment of Hygiene, Iuliu Haţieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Iuliu Hațieganu University of Medicine and Pharmacy · ROUniversity of Oradea · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe objective of the present study was to determine the association between chemotherapy and infectious complications in patients diagnosed with Hematologic malignancies (HMs). MATERIALS AND

methodsThe study included 463 patients diagnosed with HMs multiple myeloma (MM), Hodgkin's lymphoma (HL), non-HL (NHL), acute myeloid leukemia (AML), acute lymphocytic leukemia, chronic lymphocytic leukemia, and chronic myeloid leukemia, between January 2014 and June 2015. The patients were followed for 1 year after inclusion, to record the infectious complications. The collected data included age, sex, type of chemotherapy regimen, and several blood tests at admission. All patients received prophylactic treatment with antibiotics and antifungal agents. For each infection, we recorded the microbiological diagnosis and the day of occurrence since HMs diagnosis.

resultsIn patients with MM, we found that the treatment with growth factors (hazard ratio [HR] 2.2; confidence interval [CI] 95%: 1-4.6;

conclusionRegarding the chemotherapy regimen, the highest incidences of infectious complications were observed for growth factors and cytarabine.

Indexed as

Chemotherapyhematologic malignanciesinfectious complications

Identifiers

PMID30181750
PMCPMC6091125
OpenAlexW2883310458

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.