ArticleScientific reports2018
Dengue virus infection changes Aedes aegypti oviposition olfactory preferences.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 31 citations in OpenAlex.
- The impact of blood on vector-borne diseases with emphasis on mosquitoes and sand flies.Trends in parasitology · 2025Review
- Dengue-mediated changes in the vectorial capacity of Aedes aegypti (Diptera: Culicidae): manipulation of transmission or infection by-product?Journal of medical entomology · 2025Review
- Genomic Analysis ofVector borne and zoonotic diseases (Larchmont, N.Y.) · 2024Article
- Female Aedes aegypti mosquitoes use communal cues to manage population density at breeding sites.Communications biology · 2024Article
- Review
- Chikungunya Virus Infection and Gonotrophic Cycle ShapeViruses · 2023Article
- Flight behaviour monitoring and quantification of aedes aegypti using convolution neural network.PloS one · 2023Article
- Review
- Semiochemical oviposition cues to control Aedes aegypti gravid females: state of the art and proposed framework for their validation.Parasites & vectors · 2022Review
- From tissue engineering to mosquitoes: biopolymers as tools for developing a novel biomimetic approach to pest management/vector control.Parasites & vectors · 2022Review
- Dengue virus infection modifies mosquito blood-feeding behavior to increase transmission to the host.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Dengue Virus-2 Infection Affects Fecundity and Elicits Specific Transcriptional Changes in the Ovaries ofFrontiers in microbiology · 2022Article
- NO Synthesis in Immune-Challenged Locust Hemocytes and Potential Signaling to the CNS.Insects · 2021Article
- Production, Transmission, Pathogenesis, and Control of Dengue Virus: A Literature-Based Undivided Perspective.BioMed research international · 2021Review
- Behavioural and antennal responses of Aedes aegypti (l.) (Diptera: Culicidae) gravid females to chemical cues from conspecific larvae.PloS one · 2021Article
- Modulation of odour-guided behaviour in mosquitoes.Cell and tissue research · 2021Review
- Dengue infection modulates locomotion and host seeking in Aedes aegypti.PLoS neglected tropical diseases · 2020Article
- Transcriptomic Analysis ofInternational journal of molecular sciences · 2019Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aedes aegypti mosquitoes, main vectors for numerous flaviviruses, have olfactory preferences and are capable of olfactory learning especially when seeking their required environmental conditions to lay their eggs. In this study, we showed that semiochemical conditions during Aedes aegypti larval rearing affected future female choice for oviposition: water-reared mosquitoes preferred to lay eggs in water or p-cresol containers, while skatole reared mosquitoes preferred skatole sites. Using two independent behavioural assays, we showed that this skatole preference was lost in mosquitoes infected with dengue virus. Viral RNA was extracted from infected female mosquito heads, and an increase of virus load was detected from 3 to 10 days post infection, indicating replication in the insect head and possibly in the central nervous system. Expression of selected genes, potentially implied in olfactory learning processes, were also altered during dengue infection. Based on these results, we hypothesise that dengue virus infection alters gene expression in the mosquito's head and is associated with a loss of olfactory preferences, possibly modifying oviposition site choice of female mosquitoes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.