Evidence map›Paper›PMID 30181513›Full record

ArticleCancers2018

A Dietary Intervention to Lower Serum Levels of IGF-I in

Patrizia Pasanisi, Eleonora Bruno, Elisabetta Venturelli, Daniele Morelli, Andreina Oliverio, Ivan Baldassari, Francesca Rovera, Giovanna Iula, Monica Taborelli, Bernard Peissel and 2 more

Abstract read
In one paragraph

Article in Cancers, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Complex Interplay Between Obesity and BRCA1/2-Associated Breast Cancer: An Overview.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Patrizia PasanisiUnit of Epidemiology and Prevention, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, 20133 Milano, Italy. patrizia.pasanisi@istitutotumori.mi.it.
Eleonora BrunoUnit of Epidemiology and Prevention, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, 20133 Milano, Italy. eleonora.bruno@istitutotumori.mi.it.
Elisabetta VenturelliUnit of Epidemiology and Prevention, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, 20133 Milano, Italy. elisabetta.venturelli@istitutotumori.mi.it.
Daniele MorelliUnit of Laboratory Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, 20133 Milano, Italy. daniele.morelli@istitutotumori.mi.it.
Andreina OliverioUnit of Epidemiology and Prevention, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, 20133 Milano, Italy. andreina.oliverio@istitutotumori.mi.it.
Ivan BaldassariUnit of Epidemiology and Prevention, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, 20133 Milano, Italy. ivan.baldassari@istitutotumori.mi.it.
Francesca RoveraSenology Research Center-1st Division of Surgery, Department of Surgical and Morphological Sciences, University of Insubria, 21100 Varese, Italy. francesca.rovera@uninsubria.it.
Giovanna IulaSenology Research Center-ASST Spedali Civili di Brescia, 25123 Brescia, Italy. iula.giovanna@gmail.com.
Monica TaborelliGenetic Counselling Service, Institute of Oncology of Southern Switzerland (IOSI), 6500 Bellinzona, Switzerland. Monica.Taborelli@eoc.ch.ORCID 0000-0002-4293-187X
Bernard PeisselUnit of Medical Genetics, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, 20133 Milano, Italy. bernard.peissel@istitutotumori.mi.it.
Jacopo AzzoliniUnit of Medical Genetics, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, 20133 Milano, Italy. jacopo.azzolini@istitutotumori.mi.it.
Siranoush ManoukianUnit of Medical Genetics, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, 20133 Milano, Italy. siranoush.manoukian@istitutotumori.mi.it.

Funding

Associazione Italiana per la Ricerca sul Cancro IG-2015-17151Ministero della Salute GR-2010-2310116
6 · The paper itself

Abstract

backgroundInsulin-like growth factor I (IGF-I) and other markers of insulin resistance (IRm) might influence the penetrance of

methods

results213

conclusionsWomen in the intervention group showed significant improvements in IGF-I and in other IRm that might influence the penetrance of BRCA mutations.

Indexed as

BRCA genesdietIGF-Imutation carrierspenetrance

Identifiers

PMID30181513
PMCPMC6162406

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.