Evidence map›Paper›PMID 30181477›Full record

ArticleBiosensors2018

Modified Biosensor for Cholinesterase Inhibitors with Guinea Green B as the Color Indicator.

Vladimír Pitschmann, Lukáš Matějovský, Martin Lobotka, Jan Dědič, Martin Urban, Michal Dymák

Open access · goldAbstract read
In one paragraph

Article in Biosensors, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Vladimír PitschmannOritest spol. s r.o., Nábřežní 90/4, 150 00 Prague, Czech Republic. pitschmann@oritest.cz.
Lukáš MatějovskýFaculty of Environmental Technology, University of Chemistry and Technology, Technická 5, 166 28 Prague, Czech Republic. lukas.matejovsky@vscht.cz.ORCID 0000-0002-0248-4809
Martin LobotkaOritest spol. s r.o., Nábřežní 90/4, 150 00 Prague, Czech Republic. lobotka@oritest.cz.
Jan DědičNational Institute for Nuclear, Chemical and Biological Protection, Kamenná 71, 262 31 Milín, Czech Republic. dedic@sujchbo.cz.
Martin UrbanNational Institute for Nuclear, Chemical and Biological Protection, Kamenná 71, 262 31 Milín, Czech Republic. urban@sujchbo.cz.
Michal DymákNational Institute for Nuclear, Chemical and Biological Protection, Kamenná 71, 262 31 Milín, Czech Republic. dymak@sujchbo.cz.
National Institute for Nuclear, Chemical and Biological Protection · CZOritest Group (Czechia) · CZUniversity of Chemistry and Technology, Prague · CZ

Funding

Ministerstvo Vnitra České Republiky VI20152018024
6 · The paper itself

Abstract

Colorimetric biosensors of cholinesterase inhibitors are ideal for fast, reliable, and very simple detection of agents in air, in water, and on surfaces. This paper describes an innovation of the Czech Detehit biosensor, which is based on a biochemical enzymatic reaction visualized by using Ellman's reagent as a chromogenic indicator. The modification basically consists of a much more distinct color response of the biosensor, attained through optimization of the reaction system by using Guinea Green B as the indicator. The performance of the modified biosensor was verified on the chemical warfare agents (sarin, soman, cyclosarin, and VX) in water. The detection limits ascertained visually (with the naked eye) were about 0.001 µg/mL in water (exposure time 60 s, inhibition efficiency 25%).

Indexed as

Biosensing TechniquesChemical Warfare AgentsCholinesterase InhibitorsColorimetryLissamine Green DyesChemical Warfare AgentsCholinesterase Inhibitorsguinea green BLissamine Green Dyesbiosensor of cholinesterase inhibitorschemical warfare agentsenzymatic reactionGuinea Green Bvisual evaluation

Identifiers

PMID30181477
PMCPMC6164029
OpenAlexW2890666614

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.