Evidence map›Paper›PMID 30181474›Full record

ArticleInternational journal of molecular sciences2018

A Valine Mismatch at Position 129 of

Rafael Tomoya Michita, José Artur Bogo Chies, Sabine Schramm, Peter A Horn, Falko M Heinemann, Andreas Wunsch, Richard Viebahn, Peter Schenker, Vera Rebmann

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Rafael Tomoya MichitaInstitute for Transfusion Medicine, University Hospital Essen, University Duisburg-Essen, 45147 Essen, Germany. rafael.michita@gmail.com.ORCID 0000-0003-3156-9382
José Artur Bogo ChiesPost-Graduation Program in Genetics and Molecular Biology, Genetics Department, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre 91501-970, Brazil. jabchies@terra.com.br.
Sabine SchrammInstitute for Transfusion Medicine, University Hospital Essen, University Duisburg-Essen, 45147 Essen, Germany. sabine.schramm3@uk-essen.de.
Peter A HornInstitute for Transfusion Medicine, University Hospital Essen, University Duisburg-Essen, 45147 Essen, Germany. peter.horn@uk-essen.de.
Falko M HeinemannInstitute for Transfusion Medicine, University Hospital Essen, University Duisburg-Essen, 45147 Essen, Germany. falko.heinemann@uk-essen.de.
Andreas WunschDepartment of Surgery, University Hospital Knappschaftskrankenhaus Bochum, Ruhr-University Bochum, 44892 Bochum, Germany. andreas.wunsch@kk-bochum.de.
Richard ViebahnDepartment of Surgery, University Hospital Knappschaftskrankenhaus Bochum, Ruhr-University Bochum, 44892 Bochum, Germany. richard.viebahn@kk-bochum.de.
Peter SchenkerDepartment of Surgery, University Hospital Knappschaftskrankenhaus Bochum, Ruhr-University Bochum, 44892 Bochum, Germany. peter.schenker@ruhr-uni-bochum.de.ORCID 0000-0002-3607-6993
Vera RebmannInstitute for Transfusion Medicine, University Hospital Essen, University Duisburg-Essen, 45147 Essen, Germany. vera.rebmann@uk-essen.de.ORCID 0000-0003-4660-3870
University of Duisburg-Essen · DEUniversitätsklinikum Knappschaftskrankenhaus Bochum · DEUniversidade Federal do Rio Grande do Sul · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The polymorphic major histocompatibility complex class I chain-related molecule A (MICA) and its soluble form (sMICA) interact with activating receptor natural-killer group 2 member D (NKG2D) on natural-killer (NK) and T cells, thereby modifying immune responses to transplantation and infectious agents (e.g., cytomegalovirus). Two single-nucleotide polymorphisms (SNPs), rs2596538GA in the

Indexed as

Amino Acid SubstitutionAdultCytomegalovirus InfectionsFemaleGraft RejectionHistocompatibility Antigens Class IHumansKidney TransplantationMaleMiddle AgedNK Cell Lectin-Like Receptor Subfamily KPancreas TransplantationPrognosisTissue DonorsValineHistocompatibility Antigens Class IKLRK1 protein, humanMHC class I-related chain ANK Cell Lectin-Like Receptor Subfamily KValineacute and latent cytomegalovirus infectioncytomegalovirusdimorphismgenetic predispositionMICAsimultaneous pancreas–kidney transplantationsMICAVal129Met

Identifiers

PMID30181474
PMCPMC6164160
OpenAlexW2890450226

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.