Evidence map›Paper›PMID 30181472›Full record

ReviewPharmaceutics2018

Magnetogels: Prospects and Main Challenges in Biomedical Applications.

Sérgio R S Veloso, Paula M T Ferreira, J A Martins, Paulo J G Coutinho, Elisabete M S Castanheira

Abstract readReview
In one paragraph

Review in Pharmaceutics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Patterns in soft and biological matters.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2020
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sérgio R S VelosoCentre of Physics (CFUM), University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal. sergioveloso96@gmail.com.
Paula M T FerreiraCentre of Chemistry (CQ-UM), University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal. pmf@quimica.uminho.pt.
J A MartinsCentre of Chemistry (CQ-UM), University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal. jmartins@quimica.uminho.pt.
Paulo J G CoutinhoCentre of Physics (CFUM), University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal. pcoutinho@fisica.uminho.pt.ORCID 0000-0003-4426-9207
Elisabete M S CastanheiraCentre of Physics (CFUM), University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal. ecoutinho@fisica.uminho.pt.ORCID 0000-0002-5829-6081

Funding

Fundação para a Ciência e a Tecnologia UID/FIS/04650/2013; UID/QUI/00686/2016
6 · The paper itself

Abstract

Drug delivery nanosystems have been thriving in recent years as a promising application in therapeutics, seeking to solve the lack of specificity of conventional chemotherapy targeting and add further features such as enhanced magnetic resonance imaging, biosensing and hyperthermia. The combination of magnetic nanoparticles and hydrogels introduces a new generation of nanosystems, the magnetogels, which combine the advantages of both nanomaterials, apart from showing interesting properties unobtainable when both systems are separated. The presence of magnetic nanoparticles allows the control and targeting of the nanosystem to a specific location by an externally applied magnetic field gradient. Moreover, the application of an alternating magnetic field (AMF) not only allows therapy through hyperthermia, but also enhances drug delivery and chemotherapeutic desired effects, which combined with the hydrogel specificity, confer a high therapeutic efficiency. Therefore, the present review summarizes the magnetogels properties and critically discusses their current and recent biomedical applications, apart from an outlook on future goals and perspectives.

Indexed as

biomedical applicationscancer therapydrug deliveryhydrogelsmagnetic hyperthermiamagnetic nanoparticles

Identifiers

PMID30181472
PMCPMC6161300

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.