Evidence map›Paper›PMID 30181433›Full record

ArticleSensors (Basel, Switzerland)2018

Membrane-Based Microwave-Mediated Electrochemical Immunoassay for the In Vitro, Highly Sensitive Detection of Osteoporosis-Related Biomarkers.

Hye Youn Kim, Shinobu Sato, Shigeori Takenaka, Min-Ho Lee

Open access · goldAbstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 11 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Hye Youn KimSchool of Integrative Engineering, Chung-Ang University, 84 Heukseok-Ro, Dongjak-Gu, Seoul 06974, Korea. hykimbio@cau.ac.kr.
Shinobu SatoDepartment of Applied Chemistry, Research Center for Biomicrosensing Technology, Kyushu Institute of Technology, Fukuoka 804-8550, Japan. shinobu@che.kyutech.ac.jp.
Shigeori TakenakaDepartment of Applied Chemistry, Research Center for Biomicrosensing Technology, Kyushu Institute of Technology, Fukuoka 804-8550, Japan. shige@che.kyutech.ac.jp.
Min-Ho LeeSchool of Integrative Engineering, Chung-Ang University, 84 Heukseok-Ro, Dongjak-Gu, Seoul 06974, Korea. mhlee7@cau.ac.kr.ORCID 0000-0002-7028-4745
Chung-Ang University · KRKyushu Institute of Technology · JP

Funding

Ministry of Trade, Industry and Energy 10062995National Research Foundation of Korea M2018K2A9A2A08000115
6 · The paper itself

Abstract

Highly sensitive and multiplexed in vitro detection of osteoporosis-related biochemical markers were carried out based on the membrane-based microwave-mediated electrochemical immunoassay (MMeEIA), where we can dramatically reduce the sample preparation time by shortening the incubation time of conjugation to obtain sensitive detection based on three dimensional conjugation of antibodies with target antigens in nylon membrane disk. C-terminal cross-linked telopeptide of type I collagen (CTx), Osteocalcin (OC), parathyroid hormone (PTH), and N-terminal propeptide of type I collagen (P1NP), which can be utilized to monitor the progress of osteoporosis, were quantified using their corresponding antibody immobilized in membranes. Coefficient of variations in this intra- and inter-assays were within 8.0% for all markers. When compared with data obtained from clinically used standard equipment (Roche modular E170), their coefficients of determination,

Indexed as

Electrochemical TechniquesMicrowavesBiomarkersCollagen Type IHumansImmunoassayOsteocalcinOsteoporosisParathyroid HormonePeptide FragmentsProcollagenBiomarkersCollagen Type IOsteocalcinParathyroid HormonePeptide FragmentsProcollagenbone turnover markerC-terminal cross-linked telopeptide of type I collagen (CTx)membrane-based microwave-mediated electrochemical immunoassay (MMeEIA)N-terminal propeptide of type I collagen (P1NP)osteocalcin (OC)osteoporosisparathyroid hormone (PTH)

Identifiers

PMID30181433
PMCPMC6163632
OpenAlexW2892298065

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.