Evidence map›Paper›PMID 30181373›Full record

ArticleAntimicrobial agents and chemotherapy2018

Effects of PERK eIF2α Kinase Inhibitor against Toxoplasma gondii.

Leonardo Augusto, Jennifer Martynowicz, Kirk A Staschke, Ronald C Wek, William J Sullivan

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
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  5. Article
  6. Article
  7. Article
  8. The determinants regulatingFrontiers in microbiology · 2022
    Review
  9. Review
  10. Review
  11. Article
  12. Frontiers in cellular and infection microbiology · 2021
    Article
  13. Frontiers in cell and developmental biology · 2021
    Article
  14. Review
  15. Evaluation ofFrontiers in cellular and infection microbiology · 2021
    Article
  16. Article
  17. Article
  18. A Comparison of Stage Conversion in the Coccidian ApicomplexansFrontiers in cellular and infection microbiology · 2020
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Leonardo AugustoDepartment of Biochemistry & Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Jennifer MartynowiczDepartment of Microbiology & Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Kirk A StaschkeDepartment of Biochemistry & Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Ronald C WekDepartment of Biochemistry & Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
William J SullivanDepartment of Pharmacology & Toxicology, Indiana University School of Medicine, Indianapolis, Indiana, USA wjsulliv@iu.edu.ORCID 0000-0003-1823-8642
Indiana University School of Medicine

Funding

Immunology and Infectious Diseases Training ProgramT32AI060519 · NIAID · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI MARK H KAPLAN · 2004 to 2026
$6.0M
Indiana Medical Scientist/Engineer Training ProgramT32GM077229 · NIGMS · INDIANA UNIVERSITY INDIANAPOLIS · PI GASTON, BENJAMIN, HERBERT, BRITTNEY-SHEA · 2008 to 2022
$6.0M
Translational control during stage conversion of Toxoplasma, an opportunistic infection of HIV/AIDSR01AI124723 · NIAID · INDIANA UNIVERSITY INDIANAPOLIS · PI SULLIVAN, WILLIAM J, WEK, RONALD C · 2016 to 2020
$2.0M
NIAID NIH HHS R01 AI124723NIAID NIH HHS T32 AI060519NIGMS NIH HHS T32 GM077229
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCell DifferentiationCells, CulturedeIF-2 KinaseEndoplasmic ReticulumEndoplasmic Reticulum StressFemaleHumansMiceMice, Inbred BALB CParasitesPhosphorylationProtein BiosynthesisProtein Kinase InhibitorsProtein Processing, Post-TranslationalProtozoan ProteinseIF-2 KinaseProtein Kinase InhibitorsProtozoan ProteinsantiparasiticsApicomplexadrugsparasiteprotozoastress responsetranslation

Identifiers

PMID30181373
PMCPMC6201070
OpenAlexW2891119758

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.