Evidence map›Paper›PMID 30181351›Full record

ArticleInfection and immunity2018

Primary Role of Suppressor of Cytokine Signaling 1 in Mycobacterium bovis BCG Infection.

Shogo Soma, Satoru Kawai, Hiroyasu Inada, Kenta Watanabe, Satoru Mizuno, Seiichi Kato, Kazuhiro Matsuo, Yasuhiro Yasutomi

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection and immunity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Shogo SomaDepartment of Molecular and Experimental Medicine, Mie University Graduate School of Medicine, Edobashi, Tsu, Mie, Japan.
Satoru KawaiDepartment of Tropical Medicine and Parasitology, Dokkyo Medical University, Mibu, Shimotsuga, Tochigi, Japan.
Hiroyasu InadaFaculty of Pharmaceutical Science, Department of Pathology, Suzuka University of Medical Science, Minamitamagaki, Suzuka, Mie, Japan.
Kenta WatanabeJoint Faculty of Veterinary Medicine, Laboratory of Veterinary Public Health, Yamaguchi University, Oaza Yoshida, Yamaguchi, Japan.
Satoru MizunoDepartment of Molecular and Experimental Medicine, Mie University Graduate School of Medicine, Edobashi, Tsu, Mie, Japan.
Seiichi KatoLaboratory of Immunoregulation and Vaccine Research, Tsukuba Primate Research Center, National Institutes of Biomedical Innovation, Health and Nutrition, Tsukuba, Ibaraki, Japan.
Kazuhiro MatsuoResearch and Development Department, Japan BCG Laboratory, Matsuyama, Kiyose, Tokyo, Japan.
Yasuhiro YasutomiDepartment of Molecular and Experimental Medicine, Mie University Graduate School of Medicine, Edobashi, Tsu, Mie, Japan yasutomi@nibiohn.go.jp.
Japan BCG Laboratory · JPMie University · JPDokkyo Medical University · JPSuzuka University of Medical Science · JPYamaguchi University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Suppressor of cytokine signaling 1 (SOCS1) is a negative regulator of JAK/STAT signaling and is induced by mycobacterial infection. To understand the major function of SOCS1 during infection, we established a novel system in which recombinant

Indexed as

Host-Pathogen InteractionsSignal TransductionAnimalsDisease Models, AnimalHomeodomain ProteinsMice, Inbred C57BLMice, KnockoutMycobacterium bovisNitric OxideNitric Oxide Synthase Type IISuppressor of Cytokine Signaling 1 ProteinTuberculosisHomeodomain ProteinsNitric OxideNitric Oxide Synthase Type IINos2 protein, mouseRAG-1 proteinSocs1 protein, mouseSuppressor of Cytokine Signaling 1 ProteinMycobacterium bovis BCGMycobacterium tuberculosisnitric oxiderecombinant BCGSOCS1

Identifiers

PMID30181351
PMCPMC6204702
OpenAlexW2889811240

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.