Evidence map›Paper›PMID 30181253›Full record

ArticlemBio2018

Functional Conservation of P48/45 Proteins in the Transmission Stages of

Yi Cao, Robert J Hart, Geetha P Bansal, Nirbhay Kumar

Open access · goldAbstract read
In one paragraph

Article in mBio, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Molecular Characterization ofTropical medicine and infectious disease · 2025
    Article
  2. Evaluation of the transmission-blocking potential ofFrontiers in cellular and infection microbiology · 2025
    Article
  3. Article
  4. Article
  5. Cross-reactivity of rbioRxiv : the preprint server for biology · 2024
    Article
  6. Article
  7. Immunogenicity and transmission-blocking potential of quiescin sulfhydryl oxidase inFrontiers in cellular and infection microbiology · 2024
    Article
  8. The global transcriptome ofMicrobiology spectrum · 2023
    Article
  9. Article
  10. Host-parasite interactions duringFrontiers in immunology · 2022
    Review
  11. Article
  12. Review
  13. Frontiers in microbiology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yi CaoDepartment of Tropical Medicine, School of Public Health and Tropical Medicine, Tulane University, New Orleans, Louisiana, USA.
Robert J HartDepartment of Tropical Medicine, School of Public Health and Tropical Medicine, Tulane University, New Orleans, Louisiana, USA.
Geetha P BansalDepartment of Tropical Medicine, School of Public Health and Tropical Medicine, Tulane University, New Orleans, Louisiana, USA.
Nirbhay KumarDepartment of Tropical Medicine, School of Public Health and Tropical Medicine, Tulane University, New Orleans, Louisiana, USA nkumar@tulane.edu.ORCID 0000-0002-0358-4924
Tulane University · US

Funding

Combination Vaccines to Interrupt Malaria TransmissionR01AI127544 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI KUMAR, NIRBHAY · 2017 to 2020
$2.2M
Identification of Transmission blocking epitopes on P. vivax 48/45 proteinR03AI111138 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI KUMAR, NIRBHAY · 2015 to 2016
$151k
NIAID NIH HHS R01 AI127544NIAID NIH HHS R03 AI111138
6 · The paper itself

Abstract

Sexual-stage proteins have a distinct function in the mosquito vector during transmission and also represent targets for the development of malaria transmission-blocking vaccine. P48/45, a leading vaccine candidate, is critical for male gamete fertility and shows >50% similarity across various species of

Indexed as

AnimalsAntibodies, ProtozoanBlotting, WesternHumansMalariaMalaria, VivaxMiceOrganisms, Genetically ModifiedPlasmodium bergheiPlasmodium vivaxProtozoan ProteinsAntibodies, ProtozoanP48 protein, Plasmodium bergheiProtozoan ProteinsmalariaP48/45transgenictransmission

Identifiers

PMID30181253
PMCPMC6123445
OpenAlexW2892035374

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.