ArticleBlood2018
Altered patterns of global protein synthesis and translational fidelity in RPS15-mutated chronic lymphocytic leukemia.
Open access · bronzeAbstract read
In one paragraph
Article in Blood, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 56 citations in OpenAlex.
- ZNF292 mutations impair RNA and protein biosynthesis defining an adverse prognostic subset in early-stage chronic lymphocytic leukemia.Biomarker research · 2026Article
- HERC4 synergizes with USP16 to promote lung adenocarcinoma growth by augmenting protein translation via stabilizing RPS15.Oncogene · 2026Article
- Decoding cancer-associated ribosomal protein mutations: A new frontier in cancer and ribosome biology.HemaSphere · 2026Article
- RNAViruses · 2026Review
- Translational control by RPL22L1-specific ribosomes enhances DNA repair and chemoresistance.Nature communications · 2026Article
- The Nucleolus in Human Disease: Ribosome Biogenesis, Nucleolar Surveillance, and Therapeutic Opportunities.Biomolecules · 2026Review
- Article
- Mutant ribosomal protein RPS15 drives B cell malignancy through oxidative stress and genomic instability.Nature communications · 2026Article
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- The molecular map of CLL and Richter's syndrome.Seminars in hematology · 2024Review
- Alternative Wnt-signaling axis leads to a break of oncogene-induced senescence.Cell death & disease · 2024Article
- Leveraging genomics, transcriptomics and epigenomics to understand chemoimmunotherapy resistance in chronic lymphocytic leukemia.Cancer drug resistance (Alhambra, Calif.) · 2024Review
- Oncogenic MTOR Signaling Axis Compensates BTK Inhibition in a Chronic Lymphocytic Leukemia Patient with Richter Transformation: A Case Report and Review of the Literature.Acta haematologica · 2024Review
- Targeting mRNA translation aberrations: A novel approach for therapy in chronic lymphocytic leukemia.Cancer communications (London, England) · 2023Article
- Two "Edges" in Our Knowledge on the Functions of Ribosomal Proteins: The Revealed Contributions of Their Regions to Translation Mechanisms and the Issues of Their Extracellular Transport by Exosomes.International journal of molecular sciences · 2023Review
- Article
- RPS15 interacted with IGF2BP1 to promote esophageal squamous cell carcinoma development via recognizing mSignal transduction and targeted therapy · 2023Article
- Quality control ensures fidelity in ribosome assembly and cellular health.The Journal of cell biology · 2023Review
- The Role of WNT Pathway Mutations in Cancer Development and an Overview of Therapeutic Options.Cells · 2023Review
Corrections and comments
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Authors and funding
17 authors at 4 institutions in 2 countries.
Gabriel BretonesDepartamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología, Universidad de Oviedo, Oviedo, Spain.
Miguel G ÁlvarezDepartamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología, Universidad de Oviedo, Oviedo, Spain.
Javier R ArangoDepartamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología, Universidad de Oviedo, Oviedo, Spain.
David RodríguezDepartamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología, Universidad de Oviedo, Oviedo, Spain.
Ferran NadeuLymphoid Neoplasm Program, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain.
Miguel A PradoDepartment of Cell Biology, Harvard Medical School, Boston, MA.ORCID 0000-0002-4914-1619
Rafael Valdés-MasDepartamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología, Universidad de Oviedo, Oviedo, Spain.
Diana A PuenteDepartamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología, Universidad de Oviedo, Oviedo, Spain.
Joao A PauloDepartment of Cell Biology, Harvard Medical School, Boston, MA.
Julio DelgadoLymphoid Neoplasm Program, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain.
Neus VillamorLymphoid Neoplasm Program, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain.
Armando López-GuillermoLymphoid Neoplasm Program, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain.
Daniel J FinleyDepartment of Cell Biology, Harvard Medical School, Boston, MA.
Steven P GygiDepartment of Cell Biology, Harvard Medical School, Boston, MA.
Elías CampoLymphoid Neoplasm Program, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain.
Víctor QuesadaDepartamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología, Universidad de Oviedo, Oviedo, Spain.
Carlos López-OtínDepartamento de Bioquímica y Biología Molecular, Instituto Universitario de Oncología, Universidad de Oviedo, Oviedo, Spain.
Universidad de Oviedo · ESHarvard University · USHospital Clínic de Barcelona · ESConsorci Institut D'Investigacions Biomediques August Pi I Sunyer · ES
Funding
Resolving the role of nicotine-mediated phosphorylation on pancreatic fibrosisK01DK098285 · NIDDK · HARVARD MEDICAL SCHOOL · PI PAULO, JOAO A · 2013 to 2017
$638kNIDDK NIH HHS K01 DK098285
Abstract
Genomic studies have recently identified
Indexed as
MutationCell Line, TumorCohort StudiesHEK293 CellsHumansLeukemia, Lymphocytic, Chronic, B-CellMutation RatePoint MutationProtein BiosynthesisProtein DomainsRibosomal ProteinsRibosomesRibosomal Proteinsribosomal protein S15
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.