ArticleDiabetes2018
High CD8 T-Cell Receptor Clonality and Altered CDR3 Properties Are Associated With Elevated Isolevuglandins in Adipose Tissue During Diet-Induced Obesity.
Abstract read
In one paragraph
Article in Diabetes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
42 citing papers in PubMed.
- Interrupting T-Cell Memory Ameliorates Exaggerated Metabolic Response to Weight Cycling.Diabetes · 2026Article
- Adipocytes orchestrate obesity-related chronic inflammation through β2-microglobulin.Signal transduction and targeted therapy · 2025Article
- Distinct T Cell Subset Profiles and T-Cell Receptor Signatures in Metabolically Unhealthy Obesity.International journal of molecular sciences · 2025Article
- Epigenetic Regulation of Innate and Adaptive Immune Cells in Salt-Sensitive Hypertension.Circulation research · 2025Review
- B-cell immune repertoire analysis of autoimmune neurological syndromes with anti-GAD65 antibodies.Frontiers in neurology · 2025Article
- The T-cell receptor β chain CDR3 insights of bovine liver immune repertoire under heat stress.Animal bioscience · 2024Article
- Review
- Posttranslationally modified self-peptides promote hypertension in mouse models.The Journal of clinical investigation · 2024Article
- Adiposity, immunity, and inflammation: interrelationships in health and disease: a report from 24th Annual Harvard Nutrition Obesity Symposium, June 2023.The American journal of clinical nutrition · 2024Article
- Local Enrichment with Convergence of Enriched T-Cell Clones Are Hallmarks of Effective Peptide Vaccination against B16 Melanoma.Vaccines · 2024Article
- Fat-to-blood recirculation of partially dysfunctional PD-1iScience · 2024Article
- Adipose Tissue Dysfunction and Energy Balance Paradigms in People Living With HIV.Endocrine reviews · 2024Review
- Recent Advances in Understanding Peripheral and Gut Immune Cell-Mediated Salt-Sensitive Hypertension and Nephropathy.Hypertension (Dallas, Tex. : 1979) · 2024Review
- Immune cells in adipose tissue microenvironment under physiological and obese conditions.Endocrine · 2024Review
- Macrophage and T cell networks in adipose tissue.Nature reviews. Endocrinology · 2024Review
- Metaflammation in obesity and its therapeutic targeting.Science translational medicine · 2023Review
- Mechanisms of Oxidative Stress in Metabolic Syndrome.International journal of molecular sciences · 2023Review
- Obesity Is Associated with Increased FEndocrines · 2023Article
- Myeloid cell MHC I expression drives CD8Frontiers in immunology · 2023Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Wyatt J McDonnellDepartment of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, TN.
John R KoetheCenter for Translational Immunology and Infectious Disease, Vanderbilt University Medical Center, Nashville, TN.
Simon A MallalDepartment of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, TN.
Mark A PilkintonCenter for Translational Immunology and Infectious Disease, Vanderbilt University Medical Center, Nashville, TN.
Annet KiraboDivision of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN.
Magdalene K AmekaDepartment of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN.
Matthew A CottamDepartment of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN.
Alyssa H HastyVeterans Administration Tennessee Valley Healthcare System, Nashville, TN.
Arion J KennedyDepartment of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN arion.kennedy@vanderbilt.edu.ORCID 0000-0002-8443-3131
Funding
Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI STACIE B DUSETZINA · 1995 to 2026
$172.8MTranslational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9MTennessee CFAR: Implementation of Culturally Responsive Trauma-Informed Care with Youth with HIV in Memphis, TNP30AI110527 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI John Koethe · 2015 to 2026
$27.5MMULTIDISCIPLINARY TRAINING IN MOLECULAR ENDOCRINOLOGYT32DK007563 · NIDDK · VANDERBILT UNIVERSITY · PI Richard M O'Brien · 1988 to 2026
$15.9MImmunobiology of Blood and Vascular Systems Training ProgramT32HL069765 · NHLBI · VANDERBILT UNIVERSITY · PI HAWIGER, JACK J · 2002 to 2016
$6.5MThe Role of Adipose-Resident T Cells in HIV-Associated Glucose IntoleranceR01DK112262 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI KOETHE, JOHN · 2017 to 2021
$3.8MRole of Salt, Isoketal-modified Proteins and Dendritic Cells in HypertensionK01HL130497 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI KIRABO, ANNET · 2016 to 2020
$803kThe Role of Obesity and Adipocytes in Immune Activation on Antiretroviral TherapyK23AI100700 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI KOETHE, JOHN · 2012 to 2016
$600kHigh-Performance Computer Cluster for Biomedical ResearchS10OD023680 · OD · VANDERBILT UNIVERSITY · PI MEILER, JENS · 2017 to 2017
$587kThe Role of CD8+ T Cells In The Development of Nonalcoholic Fatty Liver DiseaseK01HL121010 · NHLBI · VANDERBILT UNIVERSITY · PI KENNEDY, ARION · 2014 to 2018
$565kTurnover of Adipose Tissue MacrophagesI01BX002195 · VA · VETERANS HEALTH ADMINISTRATION · PI HASTY, ALYSSA H · 2014 to 2024
–BLRD VA I01 BX002195NCI NIH HHS P30 CA068485NHLBI NIH HHS K01 HL121010NHLBI NIH HHS K01 HL130497NHLBI NIH HHS T32 HL069765NIAID NIH HHS K23 AI100700NIAID NIH HHS P30 AI110527NIDDK NIH HHS P30 DK058404NIDDK NIH HHS R01 DK112262NIDDK NIH HHS T32 DK007563NIH HHS S10 OD023680
Abstract
Adipose tissue (AT) CD4
Indexed as
Adipose TissueAnimalsCD8-Positive T-LymphocytesComplementarity Determining RegionsDiet, High-FatGlucose Tolerance TestInsulin ResistanceLiverMaleMiceObesityProstaglandinsComplementarity Determining RegionsProstaglandins
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.