Evidence map›Paper›PMID 30181139›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2018

CACHD1 is an α2δ-Like Protein That Modulates Ca

Graeme S Cottrell, Camille H Soubrane, James A Hounshell, Hong Lin, Venetia Owenson, Michael Rigby, Peter J Cox, Bryan S Barker, Matteo Ottolini, Selvi Ince and 5 more

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 40 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. The T-type calcium channelosome.Pflugers Archiv : European journal of physiology · 2024
    Review
  5. The importance of cache domains in αChannels (Austin, Tex.) · 2023
    Article
  6. Review
  7. Article
  8. Article
  9. αInternational journal of molecular sciences · 2022
    Article
  10. Article
  11. Amino acid sensor conserved from bacteria to humans.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  12. Investigation ofFrontiers in molecular neuroscience · 2022
    Article
  13. Article
  14. Article
  15. The life cycle of voltage-gated CaNeuronal signaling · 2021
    Review
  16. Article
  17. Article
  18. Neuronal Cav3 channelopathies: recent progress and perspectives.Pflugers Archiv : European journal of physiology · 2020
    Review
  19. Neuronal αPflugers Archiv : European journal of physiology · 2020
    Review
  20. Target Molecules of STIM Proteins in the Central Nervous System.Frontiers in molecular neuroscience · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 3 countries.

Graeme S CottrellUniversity of Reading, Whiteknights Campus, Reading RG6 6AJ, United Kingdom.ORCID 0000-0001-9098-7627
Camille H SoubraneUniversity of Reading, Whiteknights Campus, Reading RG6 6AJ, United Kingdom.
James A HounshellDepartments of Anesthesiology.ORCID 0000-0002-7308-2284
Hong LinUniversity of Reading, Whiteknights Campus, Reading RG6 6AJ, United Kingdom.ORCID 0000-0002-2116-590X
Venetia OwensonPfizer Neuroscience and Pain Research Unit, Granta Park, Great Abington, Cambridge CB21 6GS, United Kingdom, and.
Michael RigbyPfizer Neuroscience and Pain Research Unit, Granta Park, Great Abington, Cambridge CB21 6GS, United Kingdom, and.
Peter J CoxPfizer Neuroscience and Pain Research Unit, Granta Park, Great Abington, Cambridge CB21 6GS, United Kingdom, and.
Bryan S BarkerDepartments of Anesthesiology.ORCID 0000-0001-6808-4472
Matteo OttoliniDepartments of Anesthesiology.
Selvi InceUniversity of Reading, Whiteknights Campus, Reading RG6 6AJ, United Kingdom.
Claudia C BauerUniversity of Reading, Whiteknights Campus, Reading RG6 6AJ, United Kingdom.
Edward Perez-ReyesPharmacology, and.ORCID 0000-0001-6237-3863
Manoj K PatelDepartments of Anesthesiology.ORCID 0000-0003-3591-6716
Edward B StevensPfizer Neuroscience and Pain Research Unit, Granta Park, Great Abington, Cambridge CB21 6GS, United Kingdom, and g.j.stephens@reading.ac.uk edward.stevens@metrionbiosciences.com.
Gary J StephensUniversity of Reading, Whiteknights Campus, Reading RG6 6AJ, United Kingdom, g.j.stephens@reading.ac.uk edward.stevens@metrionbiosciences.com.ORCID 0000-0002-8966-4238
University of Reading · GBEuropean Society of Anaesthesiology · BEPfizer (United Kingdom) · GBUniversity of Virginia · US

Funding

Pathogenesis of epilepsy in a SCN8A human mutation mouse modelR01NS103090 · NINDS · UNIVERSITY OF VIRGINIA · PI PATEL, MANOJ K · 2018 to 2022
$1.8M
Sodium channels and neuronal excitability in chronic limbic epilepsy.R01NS075157 · NINDS · UNIVERSITY OF VIRGINIA · PI PATEL, MANOJ K · 2012 to 2016
$1.7M
Neuron-specific block of T-type calcium channelsR21NS069524 · NINDS · UNIVERSITY OF VIRGINIA · PI PEREZ-REYES, EDWARD · 2011 to 2012
$445k
NINDS NIH HHS R01 NS075157NINDS NIH HHS R01 NS103090NINDS NIH HHS R21 NS069524
6 · The paper itself

Abstract

The putative cache (Ca

Indexed as

AnimalsCalcium Channels, L-TypeCalcium Channels, T-TypeFemaleHEK293 CellsHippocampusHumansMaleMembrane ProteinsRatsRats, WistarCACHD1 protein, humanCacna1g protein, ratCacna2d1 protein, ratCalcium Channels, L-TypeCalcium Channels, T-TypeMembrane ProteinsCACHD1CaV3 calcium channelT-type calcium currentα2δ auxiliary subunit

Identifiers

PMID30181139
PMCPMC6199404
OpenAlexW2891274161

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.