Evidence map›Paper›PMID 30181126›Full record

ArticleJournal of bacteriology2018

Analysis of Pilin Antigenic Variation in Neisseria meningitidis by Next-Generation Sequencing.

Jing Xu, H Steven Seifert

Open access · bronzeAbstract read
In one paragraph

Article in Journal of bacteriology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Generation and Repair of Postreplication Gaps in Escherichia coli.Microbiology and molecular biology reviews : MMBR · 2023
    Review
  5. Article
  6. Altering theBiochemistry · 2020
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jing XuDepartment of Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
H Steven SeifertDepartment of Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA h-seifert@northwestern.edu.ORCID 0000-0001-8651-0375
Northwestern University · US

Funding

Mechanisms of Gonococcal Pilin Antigenic/Phase VariationR37AI033493 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Hank S. SEIFERT · 2003 to 2026
$10.1M
NIAID NIH HHS R37 AI033493Wellcome Trust R24378/CN001
6 · The paper itself

Abstract

Many pathogenic microbes evade host immune surveillance by varying the surface antigens, a process termed antigenic variation. While the process of pilin antigenic variation has been extensively studied in the human pathogen

Indexed as

Antigenic VariationHigh-Throughput Nucleotide SequencingAntigens, BacterialBacterial ProteinsFimbriae ProteinsMutationNeisseria gonorrhoeaeNeisseria meningitidisPhenotypeAntigens, BacterialBacterial ProteinsFimbriae Proteins454 sequencingantigenic variationdiversity generationgene conversionpilus

Identifiers

PMID30181126
PMCPMC6199478
OpenAlexW2890293221

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.