Evidence map›Paper›PMID 30179708›Full record

ArticleAlcohol (Fayetteville, N.Y.)2019

Processing transdermal alcohol concentration (TAC) data to detect low-level drinking.

John D Roache, Tara E Karns-Wright, Martin Goros, Nathalie Hill-Kapturczak, Charles W Mathias, Donald M Dougherty

Open access · greenAbstract read
In one paragraph

Article in Alcohol (Fayetteville, N.Y.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Observational
  4. Common and unique latent transition analysis (CULTA) as a way to examine the trait-state dynamics of alcohol intoxication.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2025
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  7. Profiles of transdermal alcohol concentration and their prediction of negative and positive alcohol-related consequences in young adults' natural settings.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2025
    Article
  8. Drinking intention-behavior links vary by affect among heavy-drinking young adults: An ecological momentary assessment and transdermal sensor study.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2025
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  13. College Students' Day-to-Day Maladaptive Drinking Responses to Stress Severity and Stressor-Related Guilt and Anger.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2024
    Article
  14. Accuracy of transdermal alcohol monitoring devices in a laboratory setting.Alcohol and alcoholism (Oxford, Oxfordshire) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

John D RoacheDepartment of Psychiatry, The University of Texas Health Science Center at San Antonio, San Antonio, TX, United States; Department of Pharmacology, The University of Texas Health Science Center at San Antonio, San Antonio, TX, United States. Electronic address: roache@uthscsa.edu.
Tara E Karns-WrightDepartment of Psychiatry, The University of Texas Health Science Center at San Antonio, San Antonio, TX, United States.
Martin GorosDepartment of Epidemiology and Biostatistics, The University of Texas Health Science Center at San Antonio, San Antonio, TX, United States.
Nathalie Hill-KapturczakDepartment of Psychiatry, The University of Texas Health Science Center at San Antonio, San Antonio, TX, United States.
Charles W MathiasDepartment of Psychiatry, The University of Texas Health Science Center at San Antonio, San Antonio, TX, United States.
Donald M DoughertyDepartment of Psychiatry, The University of Texas Health Science Center at San Antonio, San Antonio, TX, United States; Department of Pharmacology, The University of Texas Health Science Center at San Antonio, San Antonio, TX, United States.
The University of Texas Health Science Center at San Antonio · US

Funding

Leveraging Transdermal Alcohol Monitoring to Reduce Drinking among DWI DefendantsR01AA014988 · NIAAA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI DOUGHERTY, DONALD M, HILL-KAPTURCZAK, NATHALIE · 2005 to 2021
$8.6M
Training in Drug Abuse Research: Behavior and NeurobiologyT32DA031115 · NIDA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI CHARLES P FRANCE · 2011 to 2026
$5.2M
Phosphatidylethanol and Other Ethanol Consumption MarkersR01AA022361 · NIAAA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Donald M Dougherty, Nathalie Hill-Kapturczak · 2013 to 2026
$3.5M
NIAAA NIH HHS R01 AA014988NIAAA NIH HHS R01 AA022361NIDA NIH HHS T32 DA031115
6 · The paper itself

Abstract

backgroundSeveral studies have objectively quantified drinking through the use of Alcohol Monitoring System's (AMS) transdermal alcohol concentration (TAC) device known as SCRAM CAM. Criteria that AMS uses to detect drinking are known to be conservative and only reliably detect heavy drinking equivalent to 5 or more standard drinks. Our group has developed Research Rules used to process TAC data in a manner that will detect low-level and moderate drinking even though it is below the AMS criteria for detection.

methodsSixteen male and 14 female paid research volunteers wore TAC monitors for 28 days in their natural environments and responded daily to text message prompts to self-report the previous day's drinking. Current analyses describe the Research Rules that we developed and how use of those rules impacts the detection of self-reported drinking treated as the standard in sensitivity/specificity analysis.

resultsWe observed 606 occurrences of positive TAC events over a total of 867 days and processed the TAC data to retain 345 as possible drinking events, even though AMS criteria confirmed drinking for only 163 of these events. The kinds of TAC events removed or retained by our rules are illustrated as cases of low and moderate drinking days that were detected by our rules but not by the conservative AMS criteria. AMS-confirmed TAC events have a high specificity (99.8%) to detect primarily heavy drinking, but have a poor sensitivity to detect lower-level drinking and a poor specificity as an indicator of alcohol abstinence. In contrast, our Research Rules detected 100% of TAC events detected by AMS but also detected 31% of the lower-level drinking events not detected by AMS, with 91% specificity.

conclusionsReliance upon the AMS criteria for alcohol detection affords a high specificity for detection of heavy drinking but is a poor indicator of abstinence rates. In contrast, use of our Research Rules provides more sensitive means to quantify either any drinking or low-moderate levels of drinking while still maintaining good specificity.

Indexed as

Wearable Electronic DevicesAdultAlcohol DrinkingEthanolFemaleHumansMaleEthanolAlcohol consumptionHeavy drinkingLow-level drinkingSensitivitySpecificityTransdermal alcohol concentration (TAC)Transdermal alcohol monitoring

Identifiers

PMID30179708
PMCPMC6559864
OpenAlexW2889286842

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.