ArticleThe American journal of sports medicine2018
Worsening Knee Osteoarthritis Features on Magnetic Resonance Imaging 1 to 5 Years After Anterior Cruciate Ligament Reconstruction.
Article in The American journal of sports medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
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Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Muscle strength and osteoarthritis of the knee: a systematic review and meta-analysis of longitudinal studies.Skeletal radiology · 2023Pooled it
- Exercise-therapy and education for individuals one year after anterior cruciate ligament reconstruction: a pilot randomised controlled trial.BMC musculoskeletal disorders · 2021Trial
- Associations of foot and ankle characteristics with knee symptoms and function in individuals with patellofemoral osteoarthritis.Journal of foot and ankle research · 2020Trial
- Early Patellofemoral Osteoarthritis Following ACL Reconstruction: A Narrative Review.Healthcare (Basel, Switzerland) · 2026Review
- Surgical treatment of isolated cartilage lesions during anterior cruciate ligament reconstruction was associated with greater lesion stability but similar 2-year clinical outcomes: A registry-based matched-pair second-look study.Journal of experimental orthopaedics · 2026Article
- Knee Osteoarthritis on MRI in Symptomatic Young Adults After ACL Reconstruction From the SUPER-Knee Trial: Feature Prevalence and Association With Early-Stage Clinical Osteoarthritis Criteria.Orthopaedic journal of sports medicine · 2026Article
- Synovial Fluid Biomarkers Associated With Anterior Cruciate Ligament Injury and Reconstruction: A Systematic Review.Orthopaedic journal of sports medicine · 2026Review
- Knee Crepitus and Osteoarthritis Features in Young Adults Following Traumatic Knee Injury.Arthritis care & research · 2026Article
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- Symptoms indicative of early knee osteoarthritis after ACL reconstruction: descriptive analysis of the SHIELD cohort.Osteoarthritis and cartilage open · 2025Article
- Risk factors for early onset patellofemoral osteoarthritis following anterior cruciate ligament reconstruction with hamstring tendon autograft.Journal of orthopaedic surgery and research · 2024Article
- Longitudinal changes in adiposity following anterior cruciate ligament reconstruction and associations with knee symptoms and function.Osteoarthritis and cartilage open · 2024Article
- Injury prevention for women and girls playing Australian Football: programme cocreation, dissemination and early adopter coach feedback.BMJ open sport & exercise medicine · 2024Article
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- Early patello-femoral condropathy assessment through quantitative analyses via T2 mapping magnetic resonance after anterior cruciate ligament reconstruction.La Radiologia medica · 2023Article
- Persistent underloading of patellofemoral joint following hamstring autograft ACL reconstruction is associated with cartilage health.Osteoarthritis and cartilage · 2023Article
- Patellofemoral joint loading and early osteoarthritis after ACL reconstruction.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2023Article
- Baseline cartilage T1ρ and T2 predicted patellofemoral joint cartilage lesion progression and patient-reported outcomes after ACL reconstruction.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2023Article
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Authors and funding
8 authors.
Funding
Abstract
backgroundAn anterior cruciate ligament (ACL) injury is a well-established risk factor for the long-term development of radiographic osteoarthritis (OA). However, little is known about the early degenerative changes (ie, <5 years after injury) of individual joint features (ie, cartilage, bone marrow), which may be reversible and responsive to interventions. PURPOSE: To describe early degenerative changes between 1 and 5 years after ACL reconstruction (ACLR) on magnetic resonance imaging (MRI) and explore participant characteristics associated with these changes. STUDY
designCase-control study; Level of evidence, 3.
methodsSeventy-eight participants (48 men; median age, 32 years; median body mass index [BMI], 26 kg/m
resultsWorsening of cartilage defects in any compartment occurred in 40 (51%) participants. Specifically, worsening in the patellofemoral and medial and lateral tibiofemoral compartments was present in 34 (44%), 8 (10%), and 10 (13%) participants, respectively. Worsening patellofemoral and medial and lateral tibiofemoral BMLs (14 [18%], 5 [6%], and 10 [13%], respectively) and osteophytes (7 [9%], 8 [10%], and 6 [8%], respectively) were less prevalent, while 17 (22%) displayed deteriorating meniscal lesions. Worsening of at least 1 MRI-detected OA feature, in either the patellofemoral or tibiofemoral compartment, occurred in 53 (68%) participants. Radiographic OA in any compartment was evident in 5 (6%) and 16 (21%) participants at 1 and 5 years, respectively. A high BMI (>25 kg/m
conclusionHigh rates of degenerative changes occur in the first 5 years after ACLR, particularly the development and progression of patellofemoral cartilage defects. Older patients with a higher BMI may be at particular risk and should be educated about this risk.
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