Evidence map›Paper›PMID 30179278›Full record

ReviewMolecular microbiology2018

The actinobacterial WhiB-like (Wbl) family of transcription factors.

Matthew J Bush

Abstract readReview
In one paragraph

Review in Molecular microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Construction of aACS omega · 2025
    Article
  8. A new paradigm for the regulation of A40926B0 biosynthesis.Synthetic and systems biotechnology · 2025
    Article
  9. Article
  10. Evaluation of the role ofMicrobiology spectrum · 2025
    Article
  11. Overexpression of the Wbl family regulator whiDWorld journal of microbiology & biotechnology · 2025
    Article
  12. Article
  13. ACS infectious diseases · 2025
    Article
  14. Tiny but mighty: Diverse functions of uORFs that regulate gene expression.Computational and structural biotechnology journal · 2024
    Review
  15. Article
  16. Article
  17. Article
  18. WhiB-like proteins: Diversity of structure, function and mechanism.Biochimica et biophysica acta. Molecular cell research · 2024
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Matthew J BushDepartment of Molecular Microbiology, John Innes Centre, Norwich Research Park, Norwich, NR4 7UH, UK.ORCID 0000-0001-8216-0152

Funding

Biotechnology and Biological Sciences Research Council BB/J004561/1
6 · The paper itself

Abstract

The WhiB-like (Wbl) family of proteins are exclusively found in Actinobacteria. Wbls have been shown to play key roles in virulence and antibiotic resistance in Mycobacteria and Corynebacteria, reflecting their importance during infection by the human pathogens Mycobacterium tuberculosis, Mycobacterium leprae and Corynebacterium diphtheriae. In the antibiotic-producing Streptomyces, several Wbls have important roles in the regulation of morphological differentiation, including WhiB, a protein that controls the initiation of sporulation septation and the founding member of the Wbl family. In recent years, genome sequencing has revealed the prevalence of Wbl paralogues in species throughout the Actinobacteria. Wbl proteins are small (generally ~80-140 residues) and each contains four invariant cysteine residues that bind an O

Indexed as

Bacterial ProteinsCorynebacteriumGene Expression Regulation, BacterialMycobacteriumStreptomycesTranscription FactorsBacterial ProteinsTranscription FactorswhiB protein, Streptomyces

Identifiers

PMID30179278
PMCPMC6282962

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.