Evidence map›Paper›PMID 30178608›Full record

ArticlePhysiological reports2018

Lipopolysaccharide-induced inflammation does not alter muscle spindle afferent mechanosensation or sensory integration in the spinal cord of adult mice.

Dasha Zaytseva, Anusha Allawala, Joy A Franco, Shea Putnam, Adam M Abtahie, Nina Bubalo, Connor R Criddle, Tuan A Nguyen, Peter Nguyen, Shreejit Padmanabhan and 4 more

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. ISSLS Prize in Basic Science 2025: Structural changes of muscle spindles in the multifidus muscle after intervertebral disk injury are resolved by targeted activation of the muscle.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Dasha ZaytsevaDepartment of Biological Sciences, San José State University, San Jose, California.
Anusha AllawalaDepartment of Biological Sciences, San José State University, San Jose, California.
Joy A FrancoDepartment of Biological Sciences, San José State University, San Jose, California.
Shea PutnamDepartment of Biological Sciences, San José State University, San Jose, California.
Adam M AbtahieDepartment of Biological Sciences, San José State University, San Jose, California.
Nina BubaloDepartment of Biological Sciences, San José State University, San Jose, California.
Connor R CriddleDepartment of Biological Sciences, San José State University, San Jose, California.
Tuan A NguyenDepartment of Biological Sciences, San José State University, San Jose, California.
Peter NguyenDepartment of Biological Sciences, San José State University, San Jose, California.
Shreejit PadmanabhanDepartment of Biological Sciences, San José State University, San Jose, California.
Puneet SangheraDepartment of Biological Sciences, San José State University, San Jose, California.
Martina BremerDepartment of Mathematics & Statistics, San José State University, San Jose, California.
Tzvia AbramsonDepartment of Biological Sciences, San José State University, San Jose, California.
Katherine A WilkinsonDepartment of Biological Sciences, San José State University, San Jose, California.ORCID 0000-0002-2692-5533
San Jose State University · USAbbVie (United States) · US

Funding

NIGMS MARC UNDERGRADUATE RESEARCH TRAINING GRANTT34GM008253 · NIGMS · SAN JOSE STATE UNIVERSITY · PI OUVERNEY, CLEBER COSTA · 1988 to 2020
$8.4M
San Jose State University Undergraduate MBRS RISE ProgramR25GM071381 · NIGMS · SAN JOSE STATE UNIVERSITY · PI SINGMASTER, KAREN A · 2008 to 2021
$6.3M
NIGMS NIH HHS #2T34GM008253-21NIGMS NIH HHS #5R25GM71381NIGMS NIH HHS R25 GM071381NIGMS NIH HHS T34 GM008253
6 · The paper itself

Abstract

Inflammation is known to alter nervous system function, but its effect on muscle spindle afferent mechanosensation and sensory integration in the spinal cord has not been well studied. We tested the hypothesis that systemic inflammation induced by an intraperitoneal injection of the endotoxin lipopolysaccharide (LPS; 7.5 × 10

Indexed as

Mechanotransduction, CellularAnimalsFemaleH-ReflexInflammationLipopolysaccharidesMaleMiceMice, Inbred C57BLMotor NeuronsMuscle SpindlesNeurons, AfferentProprioceptionSpinal CordVibrationLipopolysaccharidesH reflexinflammationlipopolysaccharidemuscle spindle afferent

Identifiers

PMID30178608
PMCPMC6121120
OpenAlexW2890795397

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.