ArticleAging clinical and experimental research2018
Sleep, hippocampal volume, and cognition in adults over 90 years old.
Article in Aging clinical and experimental research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 28 citations in OpenAlex.
- Hainan Longevity Model, Senile Degeneration, Cognitive Disability and Healthy Longevity.Aging medicine (Milton (N.S.W)) · 2026Review
- Which Domains of Cognition in Older Adults Are Affected by Sleep Duration? A Scoping Review.Medical journal of the Islamic Republic of Iran · 2026Review
- Sleep macro-architecture, nocturnal hypoxemia, and Alzheimer's disease-related MRI patterns among diverse older adults.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Sex Differences in the Role of Sleep on Cognition in Older Adults.medRxiv : the preprint server for health sciences · 2024Article
- Sex differences in the role of sleep on cognition in older adults.Sleep advances : a journal of the Sleep Research Society · 2024Article
- No phenotypic or genotypic evidence for a link between sleep duration and brain atrophy.Nature human behaviour · 2023Article
- Sleep profile in a population of community-dwelling nonagenarians: data from the Mugello study.Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society · 2023Article
- Brain-predicted age difference mediates the association between PROMIS sleep impairment, and self-reported pain measure in persons with knee pain.Aging brain · 2023Article
- Correlations between sleep disturbance and brain structures associated with neurodegeneration in the National Alzheimer's Coordinating Center Uniform Data Set.Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia · 2022Article
- Relationship between Resting State Heart Rate Variability and Sleep Quality in Older Adults with Mild Cognitive Impairment.International journal of environmental research and public health · 2021Article
- Cardiovascular Endurance Modifies the Link between Subjective Sleep Quality and Entorhinal Cortex Thickness in Younger Adults.Medicine and science in sports and exercise · 2021Article
- Self-Reported Sleep and Executive Function in Early Primary School Children.Frontiers in psychology · 2021Article
- Duration of night sleep and cognitive performance of community older adults.Revista latino-americana de enfermagem · 2021Article
- Neuroimaging in the Oldest-Old: A Review of the Literature.Journal of Alzheimer's disease : JAD · 2021Review
- Later bedtimes predict President Trump's performance.Economics letters · 2020Article
- Later-life sleep, cognition, and neuroimaging research: an update for 2020.Current opinion in behavioral sciences · 2020Article
- Article
- Associations between self-reported sleep characteristics and incident mild cognitive impairment: The Heinz Nixdorf Recall Cohort Study.Scientific reports · 2020Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
backgroundSeveral lines of research support associations between sleep and cognition in older adults. However, there is a paucity of data regarding sleep and cognition in nonagenarians and centenarians.
aimsThe current study examined self-reported sleep quantity and sleep quality in relation to hippocampal volume and cognition in adults aged 90 and older.
methodsA total of 144 participants of The 90+ Study completed The Medical Outcomes Study sleep questionnaire. Participants reported subjective sleep duration in hours and three sleep quality factors: sleep problems, adequacy, and somnolence. Neuropsychological assessments of memory, global cognition, language, and executive function were completed, on average, 61 days from the questionnaire. Hippocampal volume on 3 T MRI, adjusted for intracranial volume, was obtained in 82 participants. We performed multiple linear regressions, controlling for age, sex, education, sleep medication, and depression, to examine sleep characteristics in relation to hippocampal volume and cognitive performance in all the subjects and then stratified by cognition.
resultsSleep duration > 8 h was associated with lower scores in tests of global cognition, memory, and executive function compared to sleep duration of 7-8 h when collapsing across cognitive status, but only with memory in cognitively impaired subjects, and not in cognitively normal subjects. CONCLUSIONS AND DISCUSSION: Long-sleep duration is associated with poorer global cognition, memory, and executive function in the oldest-old, and is only associated with memory in cognitively impaired oldest-old. Additional research is necessary to determine if sleep duration is a risk factor or a result of poor cognition in advanced age.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.