Trial reportLasers in medical science2019
Efficacy of high-intensity laser therapy in comparison with conventional physiotherapy and exercise therapy on pain and function of patients with knee osteoarthritis: a randomized controlled trial with 12-week follow up.
Trial report in Lasers in medical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 44 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of high intensity laser therapy on pain and lower extremity function in patellofemoral pain syndrome
Photobiomodulation Therapy to Reduce Pain and Inflammation in Patients With Gonarthrosis: a Multicenter Randomized, Double-blind, Placebo-controlled Clinical Trial
Who cites it
44 citing papers in PubMed, 5 syntheses or guidelines pooled it, 83 citations in OpenAlex.
- The importance of power in photobiomodulation: a systematic review and meta-analysis of high-intensity laser therapy.Frontiers in integrative neuroscience · 2026Pooled it
- Efficacy of virtual reality exercise in knee osteoarthritis rehabilitation: a systematic review and meta-analysis.Frontiers in physiology · 2024Pooled it
- A recommended exercise program appropriate for patients with knee osteoarthritis: A systematic review and meta-analysis.Frontiers in physiology · 2022Pooled it
- Is high intensity laser therapy more effective than other physical therapy modalities for treating knee osteoarthritis? A systematic review and network meta-analysis.Frontiers in medicine · 2022Pooled it
- Association of photobiomodulation therapy (PBMT) and exercises programs in pain and functional capacity of patients with knee osteoarthritis (KOA): a systematic review of randomized trials.Lasers in medical science · 2021Pooled it
- Comparison of the effectiveness of extracorporeal shock wave therapy and high-intensity laser therapy in patients with knee osteoarthritis: a single-blind randomized clinical trial.Clinical rheumatology · 2026Trial
- Multi-wave locked system laser therapy in chronic non-specific neck pain: a double-blind placebo randomized-controlled trial.European journal of physical and rehabilitation medicine · 2025Trial
- Additional effect of high-intensity laser therapy with conventional physiotherapy related to pain and function in patients with knee osteoarthritis: a randomized, double-blind, placebo-controlled, 12-week follow-up study.Lasers in medical science · 2025Trial
- The efficacy of high-intensity laser and short-wave diathermy both combined with exercises in patients with knee osteoarthritis: a randomized comparative study.Lasers in medical science · 2025Trial
- Efficacy of high intensity laser therapy versus sham laser in symptomatic knee osteoarthritis: a double-blind randomized controlled trial.Lasers in medical science · 2025Trial
- The effect of high-intensity laser therapy on pain and lower extremity function in patellofemoral pain syndrome: a single-blind randomized controlled trial.Lasers in medical science · 2024Trial
- Efficacy of hip abductors exercise training combined with repetitive transcranial magnetic stimulation on knee osteoarthritis: A randomized controlled trial.Technology and health care : official journal of the European Society for Engineering and Medicine · 2024Trial
- Evaluation of the effect of high-intensity laser therapy (HILT) on function, muscle strength, range of motion, pain level, and femoral cartilage thickness in knee osteoarthritis: randomized controlled study.Lasers in medical science · 2023Trial
- Short-Term Efficacy of High-Intensity Laser Therapy in Alleviating Pain in Patients with Knee Osteoarthritis: A Single-Blind Randomised Controlled Trial.Pain research & management · 2022Trial
- Effects of photobiomodulation and a physical exercise program on the expression of inflammatory and cartilage degradation biomarkers and functional capacity in women with knee osteoarthritis: a randomized blinded study.Advances in rheumatology (London, England) · 2021Trial
- Comparison of outpatient and inpatient spa therapy in knee osteoarthritis.International journal of biometeorology · 2021Trial
- Efficacy of high intensity laser therapy in knee osteoarthritis: a double-blind controlled randomized study.Clinical rheumatology · 2021Trial
- Limited Effects of High-Intensity Laser Therapy on Clinical and Radiographic Outcomes in Three-Year-Old Arabian Racehorses with Dorsal Metacarpal Disease.Veterinary sciences · 2026Article
- Physical Therapy-Based Realignment Strategies for Knee Osteoarthritis: A Systematic Review.Cureus · 2026Review
- Combined ultrasound-guided hyaluronic acid injections, high-power laser therapy and physiotherapy improve hip function in osteoarthritis: A randomized controlled trial.Journal of experimental orthopaedics · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Knee osteoarthritis (KOA) is one of the most common musculoskeletal disorders causing pain and functional impairment. The purpose of the study is to compare the effects of high-intensity laser therapy (HILT), conventional physical therapy (CPT), and exercise therapy (ET) on pain and function in patients with KOA. The study was designed as an assessor-blind randomized controlled trial. Ninety-three patients (aged between 50 and 75 years) with proved KOA were included and randomly allocated into three groups, and received 12 sessions of HILT, CPT, or ET. The outcomes were pain intensity measured by visual analog scale (VAS), knee flexion range of motion (FROM), timed up and go test (TUG), 6-min walk test (6MWT), and functionality of knee measured by the Western Ontario and McMaster Universities Osteoarthritis (WOMAC) questionnaire. Statistical analyses were done to compare the amounts at the baseline, immediately after treatment and after 12 weeks. HILT was significantly more effective than the other groups in decreasing the VAS, increasing FROM and improving the scores of WOMAC (total and function subscale) both after treatment and after 12 weeks. The effect of HILT and CPT on the TUG, 6MWT, and WOMAC pain subscale was not significantly different after treatment, and both were better than ET. HILT was significantly better than the others after follow-up, particularly more effective on the stiffness subscale of WOMAC. HILT combined with exercise therapy, as a useful therapeutic approach, could have positive influences on KOA patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.