Evidence map›Paper›PMID 30178351›Full record

ArticleAdvances in experimental medicine and biology2018

Guidance to Transfer 'Bench-Ready' Medical Technology into Usual Clinical Practice: Case Study - Sensors and Spectrometer Used in EPR Oximetry.

Ann Barry Flood, Victoria A Wood, Wilson Schreiber, Benjamin B Williams, Bernard Gallez, Harold M Swartz

Abstract read
In one paragraph

Article in Advances in experimental medicine and biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ann Barry FloodRadiology, Geisel School of Medicine at Dartmouth College, Hanover, NH, USA. ann.barry.flood@dartmouth.edu.
Victoria A WoodRadiology, Geisel School of Medicine at Dartmouth College, Hanover, NH, USA.
Wilson SchreiberRadiology, Geisel School of Medicine at Dartmouth College, Hanover, NH, USA.
Benjamin B WilliamsRadiation Oncology, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA.
Bernard GallezLouvain Drug Research Institute, Université catholique de Louvain, Brussels, Belgium.
Harold M SwartzRadiology, Geisel School of Medicine at Dartmouth College, Hanover, NH, USA.

Funding

Scientific and Administrative Core: Dartmouth Medical SchoolU19AI091173 · NIAID · DARTMOUTH COLLEGE · PI SWARTS, STEVEN GREGORY · 2010 to 2014
$16.3M
Project 3: Direct & Repeated Measurement of pO2 in Deep-seated Tumors using EPR OP01CA190193 · NCI · DARTMOUTH COLLEGE · PI WILLIAMS, BENJAMIN B · 2015 to 2019
$7.0M
NCI NIH HHS P01 CA190193NIAID NIH HHS U19 AI091173
6 · The paper itself

Abstract

This paper considers the critical role that academics can have in the development of clinical innovations and especially how their impact can be optimized. The focus should be on establishing the safety and efficacy of new approaches while also incorporating human factors and human use considerations into the inventions. It is very advantageous to work in concert with the end-users (operators and clinicians) to help ensure that the innovation will be useful and feasible to be incorporated into actual clinical practice as intended. This strategy enables developments to tackle real clinical needs by providing novel strategies to improve patient care while using solutions that fit into clinical practice and that are welcomed by patients and clinical staff. These principles are illustrated by a case study of the development of clinical in vivo EPR oximetry.

Indexed as

Equipment DesignInventionsBiomedical EngineeringBiomedical TechnologyHumansOximetry

Identifiers

PMID30178351
PMCPMC6126358

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.