Evidence map›Paper›PMID 30178237›Full record

ArticlePediatric nephrology (Berlin, Germany)2018

Interdialytic weight gain and vasculopathy in children on hemodialysis: a single center study.

Vasiliki Karava, Cherine Benzouid, Theresa Kwon, Marie-Alice Macher, Georges Deschênes, Julien Hogan

Abstract read
PubMed Publisher
In one paragraph

Article in Pediatric nephrology (Berlin, Germany), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Vasiliki KaravaPediatric Nephrology Department, Robert Debré Hospital, APHP, Paris, France. vasilikikarava@hotmail.fr.
Cherine BenzouidPediatric Cardiology Department, Robert Debré Hospital, APHP, Paris, France.
Theresa KwonPediatric Nephrology Department, Robert Debré Hospital, APHP, Paris, France.
Marie-Alice MacherPediatric Nephrology Department, Robert Debré Hospital, APHP, Paris, France.
Georges DeschênesPediatric Nephrology Department, Robert Debré Hospital, APHP, Paris, France.
Julien HoganPediatric Nephrology Department, Robert Debré Hospital, APHP, Paris, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIncreased interdialytic weight gain (IDWG) has been associated with poor outcomes in adults, but its impact on hemodialysis vasculopathy in children is unknown.

methodsNineteen patients (age 9 to 19 years old) with a median hemodialysis duration of 10.4 months were enrolled. Cardiovascular evaluation included left ventricular mass index (LVMI), pulse wave velocity (PWV), and carotid intima-media thickness (cIMT) measurements. PWV and cIMT were expressed as z-scores based on reference values in healthy children. Blood pressure (BP) evaluation consisted in a 24-h ambulatory BP monitoring. Mean IDGW and residual urine output during the 6 months prior to cardiovascular examination were calculated.

resultsIncreased cIMT, LVMI, and PWV was observed in 11 (57.9%), 7 (36.8%), and 5 (26.3%) patients respectively, while BP was normal in all patients. Median IDWG was 3.5% (1.8-6.7). Residual urine output and BP status did not significantly differ between patients with IDWG ≥ or < 4%. After linear regression, IDWG was correlated to cIMT z-score (r

conclusionsHigh IDWG is associated with increased cIMT in hemodialyzed children independently of BP control and dialysis vintage. This observation reinforces the importance of interventions to avoid IDWG in hemodialyzed children.

Indexed as

Carotid Intima-Media ThicknessWeight GainAdolescentAdultBlood PressureBlood Pressure Monitoring, AmbulatoryChildFemaleHumansKidney Failure, ChronicMalePulse Wave AnalysisRenal DialysisRetrospective StudiesVascular DiseasesYoung AdultCarotid intima-media thicknessHemodialysisInterdialytic weight gainPediatricVasculopathy

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.