ReviewClinical and experimental nephrology2019
Clinical epidemiology of infectious disease among patients with chronic kidney disease.
Review in Clinical and experimental nephrology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to 2 registered trials, which are not on this map. Cited by 86 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Screening of Gastrointestinal Tract Bleeding Causes Among Chronic Renal Failure Patients in Assuit University in a Single Study Center
Assessment of T-cell Response and In-vitro Proof-of-concept of T-cell Engineering in Chronic End-stage Kidney Disease Patients.
Who cites it
86 citing papers in PubMed, 2 syntheses or guidelines pooled it, 153 citations in OpenAlex.
- What are Risk Factors of Postoperative Pneumonia in Geriatric Individuals after Hip Fracture Surgery: A Systematic Review and Meta-Analysis.Orthopaedic surgery · 2023Pooled it
- Drug-Related Problems in Hospitalised Patients with Chronic Kidney Disease: A Systematic Review.Drug safety · 2021Pooled it
- Influenza vaccination reduces incidence of peripheral arterial occlusive disease in elderly patients with chronic kidney disease.Scientific reports · 2021Trial
- Urogenital Infection Risk Associated With SGLT2 Inhibitors Versus DPP-4 Inhibitors in Type 2 Diabetes and Chronic Kidney Disease: A Nationwide Target Trial Emulation.Clinical pharmacology and therapeutics · 2026Article
- Vaccination gaps and infection risk at dialysis initiation.World journal of nephrology · 2026Article
- Recombinant zoster vaccine and risk of kidney failure, cardiovascular, and mortality in patients with chronic kidney disease.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- Multi-Omics Analysis of PBMCs Revealed Distinct Biological Differences Between Hemodialysis and Peritoneal Dialysis.International journal of molecular sciences · 2026Article
- Article
- Risk factors and a prediction model of poor prognosis in patients with invasive aspergillosis in a general hospital.BMC infectious diseases · 2026Article
- Respiratory Syncytial Virus Immunization Strategies for Older Adults in Gulf Cooperation Council Countries: Expert Consensus and Recommendations.Infectious diseases and therapy · 2026Article
- Rapid Molecular Diagnostics for Bloodstream Infection in Patients with Chronic Kidney Disease.Diagnostics (Basel, Switzerland) · 2026Review
- Nontuberculous Mycobacterium Peritonitis in Patients on Peritoneal Dialysis: A Scoping Review.Microorganisms · 2026Review
- Urinary microbiota and bacterial membrane vesicles in chronic kidney disease: contribution to antimicrobial-resistant urinary tract infections.Frontiers in cellular and infection microbiology · 2026Article
- Recurrent InvasiveCase reports in nephrology · 2026Article
- Vaccination in Children with Chronic Kidney Disease: Current Status and Perspectives.Vaccines · 2025Review
- Perceptions About Influenza and COVID-19 Vaccines Among People With CKD: Findings From the Chronic Renal Insufficiency Cohort (CRIC) Study.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2025Article
- Late-onset paradoxical response 11 years after treatment of tuberculous hepatic abscesses in an HIV-negative patient: a case report and literature review.Clinical journal of gastroenterology · 2025Review
- Enhancing explainability in epidemiological predictions using fuzzy logic integrated with machine and deep learning algorithms.Scientific reports · 2025Article
- The Uptake of Influenza, Pneumococcal, Shingles, and COVID-19 Vaccines Among US Adults With and Without Kidney Disease: Findings From the Behavioral Risk Factor Surveillance System 2018-2022.Kidney medicine · 2025Article
- Social capital and its association with clinically significant depressive symptoms in patients with end-stage kidney disease in Mexico.BMC public health · 2025Article
26 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Infectious disease is recognized as an important complication among patients with end-stage renal disease, contributing to excess morbidity and health care costs. However, recent epidemiological studies have revealed that even mild to moderate stages of chronic kidney disease (CKD) substantially increase risk of infection. Regarding underlying mechanisms, evidence suggests various aspects of altered immune response in patients with CKD including impaired function of T cells, B cells and neutrophil. Multiple conditions surrounding CKD, such as older age, diabetes, and cardiovascular disease are important contributors in the increased susceptibility to infection in this population. In addition, several mechanisms impairing immune function have been hypothesized including accumulated uremic toxins, increased oxidative stress, endothelial dysfunction, low-grade inflammation, and mineral and bone disorders. In terms of prevention strategies, influenza and pneumococcal vaccines are most feasible and important. Nevertheless, the extent of vaccine utilization in CKD has not been well documented. In addition, antibody response to vaccination may be reduced in CKD patients, and thus a vaccine delivery strategy (e.g., dose and frequency) may need to be optimized among patients with CKD. Through this review, we demonstrate that infection is a major but underrecognized complication of CKD. As CKD is recognized as a serious public health issue, dedicated research is needed to better characterize the burden of infectious disease associated with CKD, understand the pathophysiology of infection in patients with CKD, and develop effective strategies to prevent infection and its sequela in this high risk population.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.