Evidence map›Paper›PMID 30178231›Full record

ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2018

Use of Andromas and Bruker MALDI-TOF MS in the identification of Neisseria.

Florence Morel, Hervé Jacquier, Marine Desroches, Vincent Fihman, Sylvain Kumanski, Emmanuelle Cambau, Jean-Winoc Decousser, Béatrice Berçot

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Whole Genome Analyses Accurately IdentifyInternational journal of molecular sciences · 2022
    Article
  3. Limitation ofJournal of clinical microbiology · 2022
    Article
  4. Article
  5. The Laboratory Diagnosis ofPathogens (Basel, Switzerland) · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Florence MorelDépartement des Agents Infectieux, Hôpitaux Universitaires Saint-Louis, Lariboisière, Fernand-Widal, APHP, Paris, France. florence.morel2@aphp.fr.ORCID http://orcid.org/0000-0003-0848-1198
Hervé JacquierDépartement des Agents Infectieux, Hôpitaux Universitaires Saint-Louis, Lariboisière, Fernand-Widal, APHP, Paris, France.
Marine DesrochesUnité de Bactériologie-Hygiène, Hôpitaux Universitaires Henri Mondor, APHP, Paris, France.
Vincent FihmanUnité de Bactériologie-Hygiène, Hôpitaux Universitaires Henri Mondor, APHP, Paris, France.
Sylvain KumanskiDépartement des Agents Infectieux, Hôpitaux Universitaires Saint-Louis, Lariboisière, Fernand-Widal, APHP, Paris, France.
Emmanuelle CambauDépartement des Agents Infectieux, Hôpitaux Universitaires Saint-Louis, Lariboisière, Fernand-Widal, APHP, Paris, France.
Jean-Winoc DecousserUnité de Bactériologie-Hygiène, Hôpitaux Universitaires Henri Mondor, APHP, Paris, France.
Béatrice BerçotDépartement des Agents Infectieux, Hôpitaux Universitaires Saint-Louis, Lariboisière, Fernand-Widal, APHP, Paris, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Through the past decade, MALDI-TOF MS has been recognized as a fast and robust tool for identification of most bacteria in clinical microbiology. However, the accuracy of this method to identify Neisseria species is still debated, and few data are available about commensal Neisseria species identification. In this study, we assessed two MALDI-TOF MS systems (Bruker Biotyper and Andromas) for the identification of 88, 18, and 29 isolates of Neisseria gonorrhoeae, Neisseria meningitidis, and commensal Neisseria species, respectively. All 88 isolates of N. gonorrhoeae were correctly identified using both systems, and most N. meningitidis and commensal Neisseria species were well identified: only 1/18 isolates of N. meningitidis was misidentified using Bruker Biotyper, and 1 isolate of Neisseria polysaccharea was misidentified as N. meningitidis using both systems. These results strengthen the possibility to use MALDI-TOF MS as a single method for Neisseria identification in routine, with excellent performance for N. gonorrhoeae identification. However, results should be interpreted prudently for N. meningitdis and commensal Neisseria species when isolated from genital and oropharyngeal samples where these both species can coexist.

Indexed as

Biological Specimen BanksHumansNeisseriaNeisseria gonorrhoeaeNeisseria meningitidisSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationSymbiosisAndromas MALDI-TOFBacterial identificationBruker Biotyper MALDI-TOFCommensal Neisseria speciesMatrix-assisted laser desorption ionization-time of flight mass spectrometryNeisseria gonorrhoeaeNeisseria meningitidis

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.